• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Severe amiodarone induced pulmonary toxicity.严重胺碘酮致肺毒性。
J Thorac Dis. 2012 Dec;4(6):667-70. doi: 10.3978/j.issn.2072-1439.2012.06.08.
2
Amiodarone-Induced Pulmonary Toxicity - A Frequently Missed Complication.胺碘酮所致肺毒性——一种常被漏诊的并发症。
Clin Med Insights Case Rep. 2016 Oct 9;9:91-94. doi: 10.4137/CCRep.S39809. eCollection 2016.
3
Amiodarone-induced Hemoptysis: A Rare Presentation of Amiodarone-induced Pulmonary Toxicity Occurs at a Low Dose.胺碘酮诱发咯血:低剂量时胺碘酮诱发肺毒性的一种罕见表现。
Cureus. 2019 Jul 31;11(7):e5289. doi: 10.7759/cureus.5289.
4
Very early onset of amiodarone-induced pulmonary toxicity.胺碘酮致肺毒性的极早发病。
Korean Circ J. 2013 Oct;43(10):699-701. doi: 10.4070/kcj.2013.43.10.699. Epub 2013 Oct 30.
5
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity.胸部计算机断层扫描评分在评估胺碘酮所致肺毒性中的诊断效用。
Korean J Intern Med. 2014 Nov;29(6):746-53. doi: 10.3904/kjim.2014.29.6.746. Epub 2014 Oct 31.
6
Early Amiodarone-Induced Pulmonary Toxicity after Endovascular Aneurysm Repair: A Case Report.血管内动脉瘤修复术后早期胺碘酮诱发的肺毒性:一例报告
Int J Angiol. 2016 Sep;25(3):189-92. doi: 10.1055/s-0034-1387170. Epub 2014 Aug 19.
7
[Early diagnosis of amiodarone-induced pulmonary toxicity: are repeated lung function tests of any value?].
Ugeskr Laeger. 1996 Jun 10;158(24):3445-7.
8
Amiodarone-induced pulmonary toxicity with an excellent response to treatment: A case report.胺碘酮所致肺毒性且治疗反应良好:一例报告
Respir Med Case Rep. 2019 Nov 29;29:100974. doi: 10.1016/j.rmcr.2019.100974. eCollection 2020.
9
Successful treatment of severe amiodarone pulmonary toxicity with polymyxin B-immobilized fiber column direct hemoperfusion.聚季铵盐-乙二胺交联纤维柱直接血液灌流成功治疗重症胺碘酮肺毒性
Chest. 2013 Apr;143(4):1146-1150. doi: 10.1378/chest.12-0994.
10
[Acute amiodarone pulmonary toxicity with low impregnation dose: case report].[低剂量胺碘酮所致急性肺毒性:病例报告]
Medwave. 2020 Aug 14;20(7):e7996. doi: 10.5867/medwave.2020.07.7996.

引用本文的文献

1
Atrial arrhythmias following lung transplantation: A state of the art review.肺移植术后房性心律失常:最新综述
World J Transplant. 2025 Jun 18;15(2):101005. doi: 10.5500/wjt.v15.i2.101005.
2
Interstitial lipoid pneumonia-A complication of intravenous administration of lipid emulsions in critically ill patients.间质性类脂性肺炎——危重症患者静脉输注脂肪乳剂的一种并发症。
Virchows Arch. 2024 Dec 19. doi: 10.1007/s00428-024-04000-6.
3
Amiodarone Therapy: Updated Practical Insights.胺碘酮治疗:最新实用见解
J Clin Med. 2024 Oct 12;13(20):6094. doi: 10.3390/jcm13206094.
4
L-Carnitine Ameliorates Amiodarone-Mediated Alveolar Damage: Oxidative Stress Parameters, Inflammatory Markers, Histological and Ultrastructural Insights.左旋肉碱改善胺碘酮介导的肺泡损伤:氧化应激参数、炎症标志物、组织学和超微结构研究
Pharmaceuticals (Basel). 2024 Jul 30;17(8):1004. doi: 10.3390/ph17081004.
5
Suppressing NLRP3 activation and PI3K/AKT/mTOR signaling ameliorates amiodarone-induced pulmonary fibrosis in rats: a possible protective role of nobiletin.抑制 NLRP3 激活和 PI3K/AKT/mTOR 信号通路可改善胺碘酮诱导的大鼠肺纤维化:川陈皮素的一种可能的保护作用。
Inflammopharmacology. 2023 Jun;31(3):1373-1386. doi: 10.1007/s10787-023-01168-2. Epub 2023 Mar 22.
6
Amiodarone Induced Concurrent Severe Hepatic and Pulmonary Injuries - A Case Report.胺碘酮诱发的同时性严重肝肺损伤——一例报告
Acta Cardiol Sin. 2022 Sep;38(5):646-649. doi: 10.6515/ACS.202209_38(5).20220327A.
7
A multicenter retrospective cohort study on predicting the risk for amiodarone pulmonary toxicity.多中心回顾性队列研究预测胺碘酮肺毒性风险。
BMC Pulm Med. 2022 Apr 5;22(1):128. doi: 10.1186/s12890-022-01926-y.
8
Acute respiratory failure on a low dose of amiodarone - is it an underdiagnosed and undertreated condition?低剂量胺碘酮引发的急性呼吸衰竭——这是一种诊断不足和治疗不足的病症吗?
Respir Med Case Rep. 2021 Sep 5;34:101500. doi: 10.1016/j.rmcr.2021.101500. eCollection 2021.
9
The protective potential of alpha lipoic acid on amiodarone-induced pulmonary fibrosis and hepatic injury in rats.α-硫辛酸对胺碘酮诱导的大鼠肺纤维化和肝损伤的保护作用。
Mol Cell Biochem. 2021 Sep;476(9):3433-3448. doi: 10.1007/s11010-021-04173-7. Epub 2021 May 10.
10
Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis.胺碘酮毒性表现为急性全身性炎症反应综合征和类似脓毒症的多器官功能衰竭。
Am J Case Rep. 2020 Oct 23;21:e926929. doi: 10.12659/AJCR.926929.

本文引用的文献

1
Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect?胺碘酮相关性肺毒性:一种被低估的严重不良反应?
Clin Res Cardiol. 2010 Nov;99(11):693-700. doi: 10.1007/s00392-010-0181-3. Epub 2010 Jul 10.
2
Amiodarone: review of pulmonary effects and toxicity.胺碘酮:肺脏效应和毒性综述。
Drug Saf. 2010 Jul 1;33(7):539-58. doi: 10.2165/11532320-000000000-00000.
3
Amiodarone-induced pulmonary toxicity mimicking acute pulmonary edema.胺碘酮致酷似急性肺水肿的肺毒性
J Cardiovasc Med (Hagerstown). 2011 May;12(5):361-5. doi: 10.2459/JCM.0b013e328334a3f4.
4
Amiodarone pulmonary toxicity.胺碘酮肺毒性。
Can Respir J. 2009 Mar-Apr;16(2):43-8. doi: 10.1155/2009/282540.
5
Amiodarone-induced pulmonary toxicity: potentially fatal, recognize early during life!
J Am Geriatr Soc. 2008 Jul;56(7):1363-5. doi: 10.1111/j.1532-5415.2008.01715.x.
6
Amiodarone-induced pulmonary toxicity.胺碘酮所致肺毒性。
Br J Clin Pharmacol. 2008 Jul;66(1):82-7. doi: 10.1111/j.1365-2125.2008.03177.x. Epub 2008 May 6.
7
Incidence and predictors of pulmonary toxicity in Japanese patients receiving low-dose amiodarone.接受低剂量胺碘酮治疗的日本患者肺部毒性的发生率及预测因素。
Circ J. 2007 Oct;71(10):1610-6. doi: 10.1253/circj.71.1610.
8
Amiodarone-induced pulmonary toxicity. Predisposing factors, clinical symptoms and treatment.胺碘酮所致肺毒性。易感因素、临床症状及治疗。
Drug Saf. 1998 May;18(5):339-44. doi: 10.2165/00002018-199818050-00003.
9
Cationic amphiphilic drug-induced phospholipidosis.阳离子两亲性药物诱导的磷脂沉积症
Toxicol Pathol. 1997 Jan-Feb;25(1):53-60. doi: 10.1177/019262339702500111.
10
Distribution of amiodarone and its metabolite, desethylamiodarone, in human tissues.
Can J Physiol Pharmacol. 1987 Mar;65(3):360-4. doi: 10.1139/y87-062.

严重胺碘酮致肺毒性。

Severe amiodarone induced pulmonary toxicity.

机构信息

Divisions of Diagnostic and Interventional Cardiology, Department of Medicine;

出版信息

J Thorac Dis. 2012 Dec;4(6):667-70. doi: 10.3978/j.issn.2072-1439.2012.06.08.

DOI:10.3978/j.issn.2072-1439.2012.06.08
PMID:23205299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3506795/
Abstract

A known complication of Amiodarone therapy is Amiodarone induced Pulmonary Toxicity (APT). Several features of this adverse effect make it difficult to diagnosis and treat. The case of a 63-year-old male with classic radiographic and histologic findings of APT is discussed. Clinical presentation, pathophysiology, diagnostic findings, and treatment strategies are reviewed. The patient was successfully managed with pulse high dose steroid therapy.

摘要

胺碘酮治疗的已知并发症是胺碘酮诱导的肺毒性(APT)。这种不良反应的几个特征使其难以诊断和治疗。讨论了一位 63 岁男性的病例,其具有 APT 的典型放射学和组织学发现。回顾了临床表现、病理生理学、诊断发现和治疗策略。患者成功地接受了脉冲大剂量类固醇治疗。