严重胺碘酮致肺毒性。
Severe amiodarone induced pulmonary toxicity.
机构信息
Divisions of Diagnostic and Interventional Cardiology, Department of Medicine;
出版信息
J Thorac Dis. 2012 Dec;4(6):667-70. doi: 10.3978/j.issn.2072-1439.2012.06.08.
Abstract
A known complication of Amiodarone therapy is Amiodarone induced Pulmonary Toxicity (APT). Several features of this adverse effect make it difficult to diagnosis and treat. The case of a 63-year-old male with classic radiographic and histologic findings of APT is discussed. Clinical presentation, pathophysiology, diagnostic findings, and treatment strategies are reviewed. The patient was successfully managed with pulse high dose steroid therapy.
摘要
胺碘酮治疗的已知并发症是胺碘酮诱导的肺毒性（APT）。这种不良反应的几个特征使其难以诊断和治疗。讨论了一位 63 岁男性的病例，其具有 APT 的典型放射学和组织学发现。回顾了临床表现、病理生理学、诊断发现和治疗策略。患者成功地接受了脉冲大剂量类固醇治疗。
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