Université de Toulouse, UPS, Centre de Recherches sur la Cognition Animale, F-31062 Toulouse Cedex 9, France.
Learn Mem. 2012 Dec 17;20(1):29-33. doi: 10.1101/lm.026906.112.
Storage of information into long-term memory (LTM) usually requires at least two waves of transcription in many species. However, there is no clear evidence of this phenomenon in insects, which are influential models for memory studies. We measured retention in honeybees after injecting a transcription inhibitor at different times before and after conditioning. We identified two separate time windows during which the transcription blockade impairs memory quantitatively and qualitatively, suggesting the occurrence of an early transcription wave (triggered during conditioning) and a later one (starting several hours after learning). Hence insects, like other species, would require two transcription waves for LTM formation.
信息存储到长期记忆（LTM）通常需要在许多物种中至少有两波转录。然而，在昆虫中没有这种现象的明确证据，而昆虫是记忆研究的重要模型。我们在不同的时间点向蜜蜂注射转录抑制剂，然后测量它们的记忆保留情况。我们发现了两个单独的时间窗口，在这两个时间窗口中，转录阻断会在数量和质量上损害记忆，这表明早期转录波（在训练期间触发）和后期转录波（在学习后几个小时开始）的发生。因此，昆虫与其他物种一样，形成 LTM 需要两波转录。
