Kumar Bagepalli Srinivas Ashok, Lakshman Kuruba, Jayaveera Korala Konta Narsimha, Shekar Devangam Sheshadri, Muragan Chinna Swamy Vel, Manoj Bachappa
Department of Pharmacognosy, Sri K.V.College of Pharmacy, Chickballapur, Karnataka, India.
Avicenna J Med Biotechnol. 2009 Oct;1(3):167-71.
Methanolic extract of whole plant of Amaranthus viridis L (MEAV), was screened for antinociceptive activity using acetic acid induced writhing test, hot plate test and tail immersion test in mice. In a similar way a screening exercise was carried out to determine the antipyretic potential of the extract using yeast induced pyrexia method in rats. Administration of the extracts was applied to both laboratory animals at the doses of 200 and 400 mg/kg body weight, respectively. The results of the statistical analysis showed that MEAV had significant (p<0.01) dose dependent antinociceptive and antipyretic properties at 200 and 400 mg/kg. Hence present investigation reveals the antinociceptive and antipyretic activities of methanolic extract of Amaranthus viridis.
对绿穗苋全株甲醇提取物（MEAV）进行了研究，采用乙酸诱导小鼠扭体试验、热板试验和尾浸试验筛选其抗伤害感受活性。以类似方式进行了一项筛选实验，使用酵母诱导大鼠发热的方法来测定该提取物的解热潜力。分别以200和400mg/kg体重的剂量将提取物给予两种实验动物。统计分析结果表明，MEAV在200和400mg/kg时具有显著（p<0.01）的剂量依赖性抗伤害感受和解热特性。因此，本研究揭示了绿穗苋甲醇提取物的抗伤害感受和解热活性。
