Escola Bahiana de Medicina e Saúde Pública, Salvador, BA, Brazil.
Arq Bras Cardiol. 2013 Jul;101(1):9-17. doi: 10.5935/abc.20130114. Epub 2013 May 31.
Birth weight (BW) is a medium- and long-term risk determinant of cardiovascular risk factors.
To assess the association between BW and cardiovascular risk factors in adolescents of the city of Salvador, Bahia state.
Cross-sectional study with comparison of BW groups. Sample comprising 250 adolescents classified according to the BMI as follows: high-normal (> 50th percentile and < 85th percentile); overweight (> 85th percentile and < 95th percentile); and obesity (> 95th percentile). The risk variables compared were as follows: waist circumference (WC); arterial blood pressure; lipid profile; glycemia; serum insulin; HOMA-IR; and metabolic syndrome. The BW was informed by parents and classified as follows: low (BW < 2,500g); normal (BW > 2,500g and < 4,000g); and high (BW > 4,000g).
One hundred and fifty-three (61.2%) girls, age 13.74 ± 2.03 years, normal BW 80.8%, low BW 8.0%, and high BW 11.2%. The high BW group as compared with the normal BW group showed a higher frequency of obesity (42.9%, p=0.005), elevated SBP and DBP (42.9%, p=0.000 and 35.7%, p=0.007, respectively), and metabolic syndrome (46.4%, p=0.002). High BW adolescents as compared with normal BW adolescents had a prevalence ratio for high SBP 3.3 (95% CI: 1.7-6.4) and obesity 2.6 (95% CI: 1.3-5.2). The WC of high BW adolescents was 83.3 ± 10.1 (p=0.038). The lipid profile showed no statistically significant differences.
Our findings suggest that obesity, elevated SBP and DBP, and metabolic syndrome during adolescence might be associated with high BW.
出生体重（BW）是心血管危险因素的中、长期决定因素。
评估巴伊亚州萨尔瓦多市青少年的 BW 与心血管危险因素之间的关系。
采用横断面研究比较 BW 组。样本包括根据 BMI 分为以下三组的 250 名青少年：高正常（>第 50 百分位且<第 85 百分位）；超重（>第 85 百分位且<第 95 百分位）；肥胖（>第 95 百分位）。比较的风险变量如下：腰围（WC）；动脉血压；血脂谱；血糖；血清胰岛素；HOMA-IR；和代谢综合征。BW 由父母告知并分为以下几类：低（BW<2500g）；正常（BW>2500g 且<4000g）；高（BW>4000g）。
153 名（61.2%）女孩，年龄 13.74±2.03 岁，正常 BW 80.8%，低 BW 8.0%，高 BW 11.2%。与正常 BW 组相比，高 BW 组肥胖的发生率更高（42.9%，p=0.005），收缩压和舒张压升高（42.9%，p=0.000 和 35.7%，p=0.007），代谢综合征（46.4%，p=0.002）。与正常 BW 青少年相比，高 BW 青少年的高血压患病率比为 3.3（95%CI：1.7-6.4），肥胖患病率比为 2.6（95%CI：1.3-5.2）。高 BW 青少年的 WC 为 83.3±10.1（p=0.038）。血脂谱无统计学差异。
我们的研究结果表明，青少年肥胖、收缩压和舒张压升高以及代谢综合征可能与高 BW 有关。
