Guangdong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, 510120 China.
Int J Med Sci. 2013 Jun 13;10(8):974-80. doi: 10.7150/ijms.5811. Print 2013.
To assess the nutritional status, combination with anthropometric measurements and modified quantitative subjective global assessment (MQSGA) was used in multi-center hemodialysis population in South China.
A cross-sectional, descriptive-analytic study was performed in 4 teaching hospitals in South China, dated from January 2010 to December 2011. Nutritional status was assessed with MQSGA and related anthropometric indexes. Serum albumin and transthyretin were also determined for nutritional assessment.
Eighty-two randomly selected hemodialysis patients participated in the nutritional assessment, of which 75 hemodialysis patients completed all assessments. The average age was 62.70 ± 14.21 years. The mean duration of hemodialysis was 3.29 ± 1.08 years. Of the included patients, 32% patients were well nourished, 60% were mild to moderately malnourished, and 8% were severely malnourished. Along with the malnutrition severity, the serum transthyretin significantly decreased. However, no obvious changes were found in serum albumin. The mean value (Mean ± SD; 25.78 ± 4.09 cm) of mid arm circumference (MAC) was negatively correlated with MQSGA (r = -0.365; P = 0.002). Body mass index (BMI) (Mean ± SD; 21.6 ± 3.1 kg/m²) was also significantly negatively correlated with MQSGA (r = -0.392; P = 0.001). The areas under the receiver operating characteristic curve were 0.664 and 0.726, respectively.
Malnutrition is very common in South China hemodialysis population. Both BMI and MAC were effective markers for assessing nutritional status.
评估营养状况，在华南地区的多中心血液透析人群中，采用人体测量学指标与改良定量主观全面评估（MQSGA）相结合的方法。
2010 年 1 月至 2011 年 12 月，在华南地区的 4 所教学医院进行了一项横断面、描述性分析研究。采用 MQSGA 及相关人体测量学指标评估营养状况，并测定血清白蛋白和转甲状腺素蛋白进行营养评估。
82 名随机选择的血液透析患者参与了营养评估，其中 75 名血液透析患者完成了所有评估。患者的平均年龄为 62.70±14.21 岁，血液透析的平均时间为 3.29±1.08 年。在纳入的患者中，32%的患者营养良好，60%的患者存在轻至中度营养不良，8%的患者存在严重营养不良。随着营养不良程度的加重，血清转甲状腺素显著降低，而血清白蛋白没有明显变化。上臂中部周长（MAC）的平均值（Mean±SD；25.78±4.09cm）与 MQSGA 呈负相关（r=-0.365，P=0.002）。体质指数（BMI）（Mean±SD；21.6±3.1kg/m²）也与 MQSGA 显著负相关（r=-0.392，P=0.001）。受试者工作特征曲线下的面积分别为 0.664 和 0.726。
华南地区血液透析人群中营养不良非常普遍。BMI 和 MAC 均是评估营养状况的有效指标。
