Kamel Marina Salah, Khosa Amardeep, Tawse-Smith Andrew, Leichter Jonathan
Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, PO Box 647, Dunedin, 9054, New Zealand,
Lasers Med Sci. 2014 Nov;29(6):1977-85. doi: 10.1007/s10103-013-1396-0. Epub 2013 Aug 2.
The aim of this narrative review was to critically evaluate in vitro studies assessing the efficacy of lasers in the bacterial decontamination of titanium implant surfaces. The MEDLINE, Web of Knowledge and Embase electronic databases were used to search for articles relating to the use of lasers in the bacterial decontamination of titanium specimen surfaces using predetermined search statements. Clinical studies, case reports, case series, review articles and animal models were excluded. Study selection was carried out independently and then cross-checked by two authors through abstract viewing. Eighteen articles were selected for full-text analysis. Erbium-doped yttrium-aluminium-garnet lasers had a wide range of powers capable of inducing bacterial decontamination. While carbon dioxide and gallium-aluminium-arsenide diode lasers demonstrated the ability to produce bacterial decontamination, the bacterial sensitivity to each varied depending on the species involved. There is no concensus on the laser type or settings that are optimal for bacterial decontamination of titanium implant surfaces as studies employ various test specimens, contamination methodologies, irradiation settings and protocols, and outcome measures resulting in limited study comparability. More investigations are required to provide guidelines for the use of laser therapy in the decontamination of implant surfaces.
本叙述性综述的目的是批判性地评估体外研究，这些研究评估了激光在钛种植体表面细菌去污方面的疗效。使用MEDLINE、Web of Knowledge和Embase电子数据库，通过预先确定的检索语句搜索与激光在钛样本表面细菌去污中的应用相关的文章。排除临床研究、病例报告、病例系列、综述文章和动物模型。研究选择由两位作者独立进行，然后通过摘要查看进行交叉核对。选择了18篇文章进行全文分析。掺铒钇铝石榴石激光具有广泛的功率范围，能够实现细菌去污。虽然二氧化碳和砷化镓铝二极管激光显示出产生细菌去污的能力，但细菌对每种激光的敏感性因所涉及的菌种而异。由于研究采用了各种测试样本、污染方法、照射设置和方案以及结果测量方法，导致研究可比性有限，因此对于钛种植体表面细菌去污的最佳激光类型或设置尚无共识。需要更多的研究来为激光疗法在种植体表面去污中的应用提供指导。
