Quantitative analysis of subfoveal choroidal thickness using enhanced depth imaging optical coherence tomography in normal eyes.

To evaluate subfoveal choroidal thickness of normal eyes with the use of the enhanced depth imaging technique of optical coherence tomography (EDI-OCT) and correlation of choroidal thickness with patient age. A retrospective analysis of 123 healthy eyes was performed. Age, gender, refractive state and spheric equivalencies were noted. Subfoveal choroidal thickness was measured and noted manually by two independent observers. A total of 72 patients (123 eyes) were included in this study. The mean age of the patients was 47.47 (15-84). The mean spheric equivalent of the refractive error was -0.24 D. According to LogMAR, the mean visual acuity was -0.006. The mean subfoveal choroidal thickness was 280.23 μm (SD ± 81.15, range 124-527 μm). The choroidal thickness showed a negative correlation with age for the subfoveal location (p = 0.000(a)). Regression analysis showed that subfoveal choroidal thickness decreased 3.14 μm for each year of age. The regression formulation was choroidal thickness = 429 - 3.14 × age. When we compared eyes according to their spheric equivalencies, there was no statistically significant correlation between spheric equivalency and subfoveal choroidal thickness. (p = 0.14). In this study, we report choroidal thickness measurement among healthy eyes within the Turkish population to demonstrate that EDI-OCT imaging can give cross-sectional information regarding the choroid, thereby facilitating quantitative imaging.