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代谢综合征患者等热量健康北欧饮食对动态血压的影响:SYSDIET 子研究的随机对照试验

Effects of an isocaloric healthy Nordic diet on ambulatory blood pressure in metabolic syndrome: a randomized SYSDIET sub-study.

机构信息

Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark.

Institute of Public Health and Clinical Nutrition, University of Eastern Finland, and Research Unit, Kuopio University Hospital, Kuopio, Finland.

出版信息

Eur J Clin Nutr. 2014 Jan;68(1):57-63. doi: 10.1038/ejcn.2013.192. Epub 2013 Oct 16.

DOI:10.1038/ejcn.2013.192
PMID:24129358
Abstract

BACKGROUND/OBJECTIVES: Dietary pattern is central in the prevention of hypertension and blood pressure (BP)-related diseases. A diet based on healthy Nordic foods may have a favourable impact on BP. The objective was to clarify whether a Nordic alternative for a healthy food pattern would have beneficial effects on ambulatory BP in subjects with metabolic syndrome (MetS).

SUBJECTS/METHODS: In total, 37 subjects were randomized to either a healthy Nordic diet or a control diet. A healthy Nordic diet embraced whole grains, rapeseed oil, berries, fruits, vegetables, fish, nuts and low-fat dairy products of Nordic origin. The mean nutrient intake in the Nordic countries formed the control diet, embracing wheat products, dairy fat-based spread and a lower intake of fruits, vegetables and fish. Diets were isoenergetic. Ambulatory BP was monitored and 24-h urine was collected before and after 12 weeks of intervention.

RESULTS

After 12 weeks, ambulatory diastolic BP (-4.4 mm Hg; P=0.001) and mean arterial pressure (-4.2 mm Hg; P=0.006) were lowered by the healthy Nordic diet compared with the control diet, whereas changes in ambulatory systolic BP did not differ significantly between diets (-3.5 mm Hg; P=0.122). Heart rate tended to be lower in those on the healthy Nordic diet (P=0.057). Urinary sodium and potassium excretions were unaffected by diets and consequently not associated with the healthy Nordic diet-induced lowering of BP.

CONCLUSIONS

Consumption of Nordic varieties of health-enhancing foods for 12 weeks decreased diastolic ambulatory BP and mean arterial pressure in subjects with features of MetS during weight-stable condition, suggesting beneficial effects of a healthy Nordic dietary pattern on ambulatory BP.

摘要

背景/目的:饮食模式是预防高血压和与血压相关疾病的核心。基于健康北欧食品的饮食可能对血压有有利影响。本研究旨在阐明代谢综合征(MetS)患者的健康北欧饮食替代方案是否对动态血压有有益影响。

受试者/方法:共有 37 名受试者被随机分配到健康的北欧饮食或对照饮食组。健康的北欧饮食包括全谷物、菜籽油、浆果、水果、蔬菜、鱼类、坚果和低脂乳制品。北欧国家的平均营养素摄入量构成了对照饮食,包括小麦制品、基于乳脂的涂抹酱以及水果、蔬菜和鱼类的摄入量较低。两种饮食均为等热量饮食。在干预 12 周前后监测动态血压并收集 24 小时尿液。

结果

12 周后,与对照饮食相比,健康的北欧饮食使动态舒张压(-4.4mmHg;P=0.001)和平均动脉压(-4.2mmHg;P=0.006)降低,而动态收缩压的变化在两种饮食之间无显著差异(-3.5mmHg;P=0.122)。健康的北欧饮食组的心率较低(P=0.057)。饮食对尿钠和钾排泄没有影响,因此与健康的北欧饮食诱导的血压降低无关。

结论

在体重稳定的情况下,摄入富含健康北欧食品的饮食 12 周可降低 MetS 特征患者的舒张压和平均动脉压,表明健康的北欧饮食模式对动态血压有益。

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