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乳制品摄入与韩国成年人代谢综合征呈负相关:韩国基因与流行病学研究的安城和安山队列研究。

Dairy product intake is inversely associated with metabolic syndrome in Korean adults: Anseong and Ansan cohort of the Korean Genome and Epidemiology Study.

机构信息

Research Institute of Insurance and Finance, Samsung Life Insurance, Seoul, Korea.

出版信息

J Korean Med Sci. 2013 Oct;28(10):1482-8. doi: 10.3346/jkms.2013.28.10.1482. Epub 2013 Sep 25.

Abstract

The objective of this study was to examine the relationship between dairy product intake and the incidence of metabolic syndrome (MetS) and its components among middle-aged Koreans. We examined 7,240 adults aged 40-69 yr without MetS at baseline over a 45.5-month follow-up period. They were taken from the Anseong and Ansan cohort of the Korean Genome and Epidemiology Study. Dairy product intake including milk, yogurt, and cheese was assessed with food frequency questionnaire. At the follow-up, the incidence of MetS was 17.1%. The incidences of MetS components were as follows: low HDL cholesterol (16.2%), abdominal obesity (14.0%), hypertriglyceridemia (13.8%), hyperglycemia (13.3%), and hypertension (13.1%). Adjusting for potential confounders, dairy product consumption frequency was inversely associated with the risk of MetS and abdominal obesity. Hazard ratio (HR) (95% confidence interval) for dairy product consumption more than 7 times/week compared to never was 0.75 (0.64-0.88, P for trend < 0.001) for MetS and 0.73 (0.61-0.88, P for trend < 0.001) for abdominal obesity. HR for milk intake was 0.79 for MetS and 0.82 for abdominal obesity. The results of this study suggest that daily intake of dairy products protects against the development of MetS, particularly abdominal obesity, in middle-aged Koreans.

摘要

本研究旨在探讨乳制品摄入与中年韩国人代谢综合征(MetS)及其组分发生的关系。我们对基线时无 MetS 的 7240 名 40-69 岁成年人进行了 45.5 个月的随访。他们来自韩国基因组与流行病学研究的安城和安山队列。乳制品摄入(包括牛奶、酸奶和奶酪)通过食物频率问卷进行评估。随访期间,MetS 的发生率为 17.1%。MetS 组分的发生率如下:低 HDL 胆固醇(16.2%)、腹部肥胖(14.0%)、高三酰甘油血症(13.8%)、高血糖(13.3%)和高血压(13.1%)。调整潜在混杂因素后,乳制品消费频率与 MetS 和腹部肥胖的风险呈负相关。与从不食用相比,每周食用乳制品超过 7 次的 MetS 和腹部肥胖的 HR(95%CI)分别为 0.75(0.64-0.88,P 趋势 <0.001)和 0.73(0.61-0.88,P 趋势 <0.001)。牛奶摄入量的 HR 为 MetS 0.79 和腹部肥胖 0.82。本研究结果表明,每日摄入乳制品可预防中年韩国人代谢综合征的发生,特别是腹部肥胖。

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