Schwerin M, Schonfeld S, Drozdovitch V, Akimzhanov K, Aldyngurov D, Bouville A, Land C, Luckyanov N, Mabuchi K, Semenova Y, Simon S, Tokaeva A, Zhumadilov Z, Potischman N
1RTI International, Research Triangle Park, Durham, NC, USA.
2National Cancer Institute - Division of Cancer Epidemiology and Genetics, Bethesda, MD, USA.
J Dev Orig Health Dis. 2010 Jun;1(3):192-202. doi: 10.1017/S2040174410000243.
From 1949 to 1962, residents of several villages in Kazakhstan received substantial doses of radiation to the thyroid gland resulting from nuclear tests conducted at the Semipalatinsk Nuclear Test Site. The primary source of radiation was internal from an intake of radioactive iodine by consumption of contaminated dairy products. A previous research study of childhood exposure and thyroid disease in this region gathered limited data on study participants' dairy intake at the time of the fallout for the purpose of estimating past radiation doses. As many participants were too young at the time of the nuclear tests to recall dietary consumption and existing sources of archival data are limited, it was necessary to interview parents and other village residents who cared for children during this time - older adults ranging in age from 75 to 90 years. Results from 11 focus group interviews conducted in 2007 with 82 women from 4 villages in Kazakhstan yielded group-level estimates of age-, gender-, ethnicity- and village-specific dairy consumption patterns in rural Kazakhstan during the 1950s. Children typically consumed cow's milk with limited consumption of mare, goat and sheep milk; and consumed dairy products such as sour milk (airan), soft cottage cheese (tvorog) and fermented mare milk (koumiss) with the greatest amounts of koumiss reported at ages 15-21 years. The consumption patterns differed by age, and between Kazakh and Russian children, which should lead to different estimates of radiation exposure to the thyroid. This study showed the utility of focus groups to obtain quantitative estimates for dietary intake in the distant past.
从1949年到1962年,哈萨克斯坦几个村庄的居民因在塞米巴拉金斯克核试验场进行的核试验而受到大量甲状腺辐射。辐射的主要来源是通过食用受污染的乳制品摄入放射性碘而导致的体内辐射。此前一项关于该地区儿童暴露与甲状腺疾病的研究,为了估算过去的辐射剂量,收集了研究参与者在放射性尘埃沉降时乳制品摄入量的有限数据。由于许多参与者在核试验时年龄太小,无法回忆起饮食消费情况,而且现有的档案数据来源有限,因此有必要采访当时照顾孩子的父母和其他村民——年龄在75岁至90岁之间的老年人。2007年对哈萨克斯坦4个村庄的82名女性进行了11次焦点小组访谈,结果得出了20世纪50年代哈萨克斯坦农村按年龄、性别、种族和村庄划分的特定乳制品消费模式的群体层面估计。儿童通常饮用牛奶,饮用马奶、羊奶和绵羊奶的量有限;并食用酸奶(艾然)、软凝乳干酪(特沃洛格)和发酵马奶(库米斯)等乳制品,其中15至21岁的人报告饮用库米斯的量最大。消费模式因年龄以及哈萨克族和俄罗斯族儿童的不同而有所差异,这会导致对甲状腺辐射暴露的不同估计。这项研究表明了焦点小组在获取遥远过去饮食摄入量定量估计方面的实用性。