美国 2009 年 H1N1 流感疫情：量化学校开学对繁殖数的影响。
The US 2009 A(H1N1) influenza epidemic: quantifying the impact of school openings on the reproductive number.
机构信息
From the aDepartment of Epidemiology, Center for Communicable Disease Dynamics, Harvard School of Public Health, Boston, MA; bDepartment of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, MA; and cDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY.
出版信息
Epidemiology. 2014 Mar;25(2):203-6. doi: 10.1097/EDE.0000000000000055.
Abstract
BACKGROUND
There is limited information on differences in the dynamics of influenza transmission during time periods when schools are open compared with periods when they are closed.
METHODS
Data on school openings, influenza surveillance, and absolute humidity were incorporated into a regression model to estimate the increase in the reproductive number for the 2009 A(H1N1) influenza pandemic associated with the opening of school in 10 US states.
RESULTS
The estimate for the average increase in the reproductive number for the 2009 A(H1N1) influenza pandemic associated with the beginning of the school year was 19.5% (95% credible interval = 10%-29%).
CONCLUSIONS
Whether schools are open or closed can have a major impact on community transmission dynamics of influenza.
摘要
背景
关于学校开放期间与关闭期间流感传播动态的差异，相关信息有限。
方法
将学校开放、流感监测和绝对湿度数据纳入回归模型，以估计与美国 10 个州的学校开学相关的 2009 年 A(H1N1)流感大流行的繁殖数增加情况。
结果
与学年开始相关的 2009 年 A(H1N1)流感大流行的繁殖数平均增加估计值为 19.5%（95%可信区间=10%-29%）。
结论
学校开放或关闭都可能对流感在社区的传播动态产生重大影响。
相似文献
1
The US 2009 A(H1N1) influenza epidemic: quantifying the impact of school openings on the reproductive number.美国 2009 年 H1N1 流感疫情：量化学校开学对繁殖数的影响。
Epidemiology. 2014 Mar;25(2):203-6. doi: 10.1097/EDE.0000000000000055.
2
School opening dates predict pandemic influenza A(H1N1) outbreaks in the United States.开学日期可预测美国的甲型 H1N1 流感大流行。
J Infect Dis. 2010 Sep 15;202(6):877-80. doi: 10.1086/655810.
3
Effects of school closure on incidence of pandemic influenza in Alberta, Canada.学校关闭对加拿大阿尔伯塔省大流行性流感发病率的影响。
Ann Intern Med. 2012 Feb 7;156(3):173-81. doi: 10.7326/0003-4819-156-3-201202070-00005.
4
Spatial Transmission of 2009 Pandemic Influenza in the US.2009年美国甲型H1N1流感大流行的空间传播
PLoS Comput Biol. 2014 Jun 12;10(6):e1003635. doi: 10.1371/journal.pcbi.1003635. eCollection 2014 Jun.
5
Transmission dynamics of the 2009 influenza A (H1N1) pandemic in India: the impact of holiday-related school closure.印度 2009 年甲型 H1N1 流感大流行的传播动力学：与假期相关的学校关闭的影响。
Epidemics. 2013 Dec;5(4):157-63. doi: 10.1016/j.epidem.2013.08.001. Epub 2013 Aug 28.
6
Characterizing the epidemiology of the 2009 influenza A/H1N1 pandemic in Mexico.描述墨西哥 2009 年甲型 H1N1 流感大流行的流行病学特征。
PLoS Med. 2011 May;8(5):e1000436. doi: 10.1371/journal.pmed.1000436. Epub 2011 May 24.
7
Spatial and temporal characteristics of the 2009 A/H1N1 influenza pandemic in Peru.秘鲁 2009 年甲型 H1N1 流感大流行的时空特征。
PLoS One. 2011;6(6):e21287. doi: 10.1371/journal.pone.0021287. Epub 2011 Jun 21.
8
Different transmission patterns in the early stages of the influenza A(H1N1)v pandemic: a comparative analysis of 12 European countries.甲型 H1N1 流感大流行早期的不同传播模式：12 个欧洲国家的比较分析。
Epidemics. 2011 Jun;3(2):125-33. doi: 10.1016/j.epidem.2011.03.005. Epub 2011 Apr 13.
9
Summaries for patients: Effects of school closure on incidence of pandemic influenza in Alberta, Canada.患者摘要：加拿大艾伯塔省学校关闭对甲型H1N1流感大流行发病率的影响。
Ann Intern Med. 2012 Feb 7;156(3):I28. doi: 10.7326/0003-4819-156-3-201202070-00001.
10
School closure and mitigation of pandemic (H1N1) 2009, Hong Kong.学校停课与 2009 年大流行（H1N1）流感的缓解，香港。
Emerg Infect Dis. 2010 Mar;16(3):538-41. doi: 10.3201/eid1603.091216.
引用本文的文献
1
Estimated COVID-19 Periodicity and Correlation with SARS-CoV-2 Spike Protein S1 Antigenic Diversity, United States.美国新冠病毒病（COVID-19）的估计周期性及其与严重急性呼吸综合征冠状病毒2（SARS-CoV-2）刺突蛋白S1抗原多样性的相关性
Emerg Infect Dis. 2025 Aug;31(8):1573-1579. doi: 10.3201/eid3108.250451.
2
Vacation and back-to-school effect on influenza transmission among school-age children in Guangzhou, China: an ecological study from 2010 to 2023.中国广州学龄儿童假期和返校对流感传播的影响：一项2010年至2023年的生态学研究
BMJ Open. 2025 Jun 23;15(6):e096341. doi: 10.1136/bmjopen-2024-096341.
3
The role of place-based factors and other social determinants of health on adverse post-sepsis outcomes: a review of the literature.基于地点的因素及其他健康社会决定因素对脓毒症后不良结局的作用：文献综述
Front Disaster Emerg Med. 2024;2. doi: 10.3389/femer.2024.1357806. Epub 2024 Feb 29.
4
Age-dependent heterogeneity in the antigenic effects of mutations to influenza hemagglutinin.流感血凝素突变的抗原效应在年龄依赖性方面存在异质性。
Cell Host Microbe. 2024 Aug 14;32(8):1397-1411.e11. doi: 10.1016/j.chom.2024.06.015. Epub 2024 Jul 19.
5
The effect of smaller classes on infection-related school absence: evidence from the Project STAR randomized controlled trial.小班教学对感染相关的学校缺勤的影响：来自 STAR 项目随机对照试验的证据。
BMC Public Health. 2024 Jan 3;24(1):83. doi: 10.1186/s12889-023-17503-9.
6
Unequal Opportunity Spreaders: Higher COVID-19 Deaths with Later School Closure in the United States.机会不均等的传播者：美国学校关闭时间较晚导致新冠死亡人数更多
Sociol Perspect. 2021 Oct;64(5):831-856. doi: 10.1177/07311214211005486. Epub 2021 Apr 9.
7
Impact of public health interventions to curb SARS-CoV-2 spread assessed by an evidence-educated Delphi panel and tailored SEIR model.由一个基于证据的德尔菲小组和定制的SEIR模型评估公共卫生干预措施对遏制SARS-CoV-2传播的影响。
Z Gesundh Wiss. 2023;31(4):539-552. doi: 10.1007/s10389-021-01566-2. Epub 2021 May 17.
8
Social distancing and testing as optimal strategies against the spread of COVID-19 in the Rio Grande Valley of Texas.社交距离和检测作为德克萨斯州里奥格兰德河谷地区应对新冠病毒传播的最优策略。
Infect Dis Model. 2021;6:729-742. doi: 10.1016/j.idm.2021.04.004. Epub 2021 Apr 24.
9
Strategies to exiting the COVID-19 lockdown for workplace and school: A scoping review.工作场所和学校解除新冠疫情封锁的策略：一项范围综述。
Saf Sci. 2021 Feb;134:105067. doi: 10.1016/j.ssci.2020.105067. Epub 2020 Oct 31.
10
Dynamic Propagation and Impact of Pandemic Influenza A (2009 H1N1) in Children: A Detailed Review.甲型H1N1流感大流行在儿童中的动态传播及影响：详细综述
Curr Microbiol. 2020 Dec;77(12):3809-3820. doi: 10.1007/s00284-020-02213-x. Epub 2020 Sep 21.
本文引用的文献
1
School closures and influenza: systematic review of epidemiological studies.学校关闭与流感：流行病学研究的系统综述。
BMJ Open. 2013 Feb 26;3(2). doi: 10.1136/bmjopen-2012-002149. Print 2013.
2
Prevalence of seropositivity to pandemic influenza A/H1N1 virus in the United States following the 2009 pandemic.2009 年大流行后美国人群中抗大流行流感 A/H1N1 病毒血清阳性率。
PLoS One. 2012;7(10):e48187. doi: 10.1371/journal.pone.0048187. Epub 2012 Oct 31.
3
Robust reconstruction and analysis of outbreak data: influenza A(H1N1)v transmission in a school-based population.稳健的暴发数据重建与分析：基于学校人群的甲型 H1N1 流感传播。
Am J Epidemiol. 2012 Aug 1;176(3):196-203. doi: 10.1093/aje/kws006. Epub 2012 Jul 12.
4
Effects of school closure on incidence of pandemic influenza in Alberta, Canada.学校关闭对加拿大阿尔伯塔省大流行性流感发病率的影响。
Ann Intern Med. 2012 Feb 7;156(3):173-81. doi: 10.7326/0003-4819-156-3-201202070-00005.
5
Predicting the epidemic sizes of influenza A/H1N1, A/H3N2, and B: a statistical method.预测甲型流感 A/H1N1、A/H3N2 和 B 的流行规模：一种统计方法。
PLoS Med. 2011 Jul;8(7):e1001051. doi: 10.1371/journal.pmed.1001051. Epub 2011 Jul 5.
6
Different transmission patterns in the early stages of the influenza A(H1N1)v pandemic: a comparative analysis of 12 European countries.甲型 H1N1 流感大流行早期的不同传播模式：12 个欧洲国家的比较分析。
Epidemics. 2011 Jun;3(2):125-33. doi: 10.1016/j.epidem.2011.03.005. Epub 2011 Apr 13.
7
School opening dates predict pandemic influenza A(H1N1) outbreaks in the United States.开学日期可预测美国的甲型 H1N1 流感大流行。
J Infect Dis. 2010 Sep 15;202(6):877-80. doi: 10.1086/655810.
8
Absolute humidity and the seasonal onset of influenza in the continental United States.美国大陆地区的绝对湿度与流感季节性发病的关系。
PLoS Biol. 2010 Feb 23;8(2):e1000316. doi: 10.1371/journal.pbio.1000316.
9
Household transmission of 2009 pandemic influenza A (H1N1) virus in the United States.家庭传播的 2009 年流感大流行的甲型 H1N1 病毒在美国。
N Engl J Med. 2009 Dec 31;361(27):2619-27. doi: 10.1056/NEJMoa0905498.
10
Economic cost and health care workforce effects of school closures in the U.S.美国学校关闭的经济成本及对医疗保健劳动力的影响
PLoS Curr. 2009 Oct 5;1:RRN1051. doi: 10.1371/currents.rrn1051.
Zotero 插件