M.M. Rahman, Department of Medical Microbiology & Immunology, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
K.K. Wong, Department of Medical Microbiology & Immunology, University Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.
Pak J Med Sci. 2014 Jan;30(1):161-5. doi: 10.12669/pjms.301.4272.
Respiratory infections represent a major public health problem worldwide. The study aimed to determine the prevalence of respiratory syncytial and influenza virus infections and analyzed in respect to demography and clinical perspective. Methods : The specimens were processed by cell culture and immunofluorescent assay (IFA) and real-time reverse transcriptase-PCR (rRT-PCR) for detection of respiratory viruses. Results : Out of 505 specimens 189 (37.8%) were positive, in which RSV was positive in 124(24.8%) cases and influenza A was positive in 65(13%) cases. Positive cases for influenza virus A and RSV were analyzed based on demography: age, gender, ethnicity and clinical symptoms. There were no significant differences among gender, ethnicity and clinical symptoms in both RSV and influenza A virus infections. It was observed that children below 3 years of ages were more prone to RSV infections. On the contrary, influenza virus A infected all age groups of humans.
RSV infects mostly child below 3 years of age and influenza virus infects all age group. No specificity of RSV and influenza infection in relation to demography.
呼吸道感染是全球主要的公共卫生问题。本研究旨在确定呼吸道合胞病毒和流感病毒感染的流行率，并从人口统计学和临床角度进行分析。
通过细胞培养和免疫荧光检测（IFA）以及实时逆转录聚合酶链反应（rRT-PCR）对呼吸道病毒进行检测。
在 505 份标本中，有 189 份（37.8%）为阳性，其中 RSV 阳性 124 例（24.8%），甲型流感阳性 65 例（13%）。根据人口统计学：年龄、性别、种族和临床症状，对甲型流感病毒和 RSV 的阳性病例进行了分析。在 RSV 和流感 A 病毒感染中，性别、种族和临床症状之间没有显著差异。观察到 3 岁以下儿童更容易感染 RSV。相反，流感病毒 A 感染了所有年龄段的人类。
RSV 主要感染 3 岁以下儿童，流感病毒感染所有年龄组。RSV 和流感感染与人口统计学无关，没有特异性。
