Elkhateeb Ahmed, El-Beih Ahmed A, Gamal-Eldeen Amira M, Alhammady Montaser A, Ohta Shinji, Paré Paul W, Hegazy Mohamed-Elamir F
Phytochemistry and Plant Systematic Department, National Research Centre, El-Tahrir St., Dokki, Giza 12311, Egypt.
Department of Chemistry of Natural & Microbial Products, Center of Excellence Advanced Sciences, National Research Centre, El-Tahrir Street, Dokki, Giza 12311, Egypt.
Mar Drugs. 2014 Apr 2;12(4):1977-86. doi: 10.3390/md12041977.
Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1-3 as well as the previously reported marine cembranoid diterpene sarcophine (4). Structures were elucidated by comprehensive NMR and HRMS experimentation. Isolated compounds were in vitro assayed for cytotoxic activity against human hepatocarcinoma (HepG2) and breast adenocarcinoma (MCF-7) cell lines.
对埃及软珊瑚艾氏肉芝软珊瑚进行的化学研究已分离出化合物1 - 3以及先前报道的海洋西松烷型二萜类化合物肉芝素（4）。通过全面的核磁共振（NMR）和高分辨率质谱（HRMS）实验阐明了其结构。对分离出的化合物进行了体外实验，检测其对人肝癌（HepG2）和乳腺腺癌（MCF - 7）细胞系的细胞毒性活性。
