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家庭支持改善行为对2型糖尿病患者抗糖尿病药物依从性及认知的影响

Impact of family support improvement behaviors on anti diabetic medication adherence and cognition in type 2 diabetic patients.

作者信息

Khosravizade Tabasi Hamidreza, Madarshahian Farah, Khoshniat Nikoo Mohsen, Hassanabadi Mohsen, Mahmoudirad Gholamhossein

机构信息

Birjand University of Medical Sciences, Ghafary Ave., Birjand, 9717853577 Iran.

Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, North Kargar Street, Tehran, 1411413137 Iran.

出版信息

J Diabetes Metab Disord. 2014 Nov 25;13(1):113. doi: 10.1186/s40200-014-0113-2. eCollection 2014.

Abstract

BACKGROUND

Glycaemic control is the main goal of treatment for type 2 diabetic patients. Hyperglycaemia may result in cognitive decline. More family support may increase medication adherence and decrease glycaemic level. The purpose of this study was to determine the impact of family support improvement behavior on anti diabetic medication adherence and cognition in type 2 diabetic patients.

METHOD

The randomized control trial study was conducted on 91 patients from an outpatient diabetes clinic. They were randomly divided to intervention (n = 45) and control (n = 46) group. Data on the patients' demographic information and their family gathered using a questionnaire, For two groups Morisky Medication Adherence Scale (MMAS), drug administration part of Diabetes Social Support Questionnaire - family version (DSSQ), Number Connection Test (NCT) were applied and hemoglobin A1C was measured two times in the onset of study and three months later for control group and before and after intervention for intervention group. The key family members of the intervention group were taught according to their educational needs in small groups.

RESULT

In intervention group mean of NCT score was significantly decreased after intervention (P = 0.006) however in the control group there was no significant difference after three months. In intervention group a significant correlation was noted between DSSQ scores and MMAS scores after intervention(r =0.67, P < 0.001) but, there was no significant correlation in the control group.

CONCLUSION

Family support instruction based on the educational needs of family members, may improve medication adherence through direct effect and cognitive status with indirect effect.

摘要

背景

血糖控制是2型糖尿病患者治疗的主要目标。高血糖可能导致认知能力下降。更多的家庭支持可能会提高药物依从性并降低血糖水平。本研究的目的是确定改善家庭支持行为对2型糖尿病患者抗糖尿病药物依从性和认知的影响。

方法

对一家门诊糖尿病诊所的91名患者进行随机对照试验研究。他们被随机分为干预组(n = 45)和对照组(n = 46)。使用问卷收集患者及其家庭的人口统计学信息。对两组应用Morisky药物依从性量表(MMAS)、糖尿病社会支持问卷 - 家庭版(DSSQ)的药物管理部分、数字连接测试(NCT),并在研究开始时和三个月后对对照组以及干预组干预前后测量糖化血红蛋白A1C。根据干预组关键家庭成员的教育需求进行小组授课。

结果

干预组干预后NCT评分均值显著降低(P = 0.006),而对照组三个月后无显著差异。干预组干预后DSSQ评分与MMAS评分之间存在显著相关性(r = 0.67,P < 0.001),但对照组无显著相关性。

结论

基于家庭成员教育需求的家庭支持指导,可能通过直接作用改善药物依从性,并通过间接作用改善认知状态。

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