口服姜黄凝胶在牙龈炎治疗中的效果——一项初步研究。
Effect of oral curcuma gel in gingivitis management - a pilot study.
作者信息
Farjana H Nilofer, Chandrasekaran S C, Gita Bagavad
机构信息
Post Graduate, Department of Periodontology, Bharat University, Sree Balaji Dental College and Hospital , Chennai, India .
HOD Professor, Department of Periodontology, Bharat University, Sree Balaji Dental College and Hospital , Chennai, India .
出版信息
J Clin Diagn Res. 2014 Dec;8(12):ZC08-10. doi: 10.7860/JCDR/2014/8784.5235. Epub 2014 Dec 5.
BACKGROUND
Various modalities of treatments are available for gingival disease, but there are adverse effects of these conventional compounds. This led to the search of natural products which are highly beneficial and biocompatible. Turmeric is one such novel product obtained from plants, known for its varied medicinal value. In dentistry, it plays a role treating gingival and periodontal disease.
AIM
To evaluate the clinical efficacy of oral curcuma gel in gingivitis and to assess any adverse effects of the gel.
MATERIALS AND METHODS
This pilot study comprises of 10 individuals with severe gingivitis. They were made to apply oral curcuma gel for a period of 21 days. The papillary bleeding index (PBI) were assessed before and after along with visual analogue scale. The obtained data was statistically analysed.
RESULTS
The data was analysed with Pearson Spearman's correlation coefficient and paired 't' test. The results were statistically significant with p<0.001.
CONCLUSION
The gel containing curcuma longa extract was efficient in treating gingivitis by reducing its inflammatory components.
背景
牙龈疾病有多种治疗方式，但这些传统化合物存在不良反应。这促使人们寻找具有高度益处和生物相容性的天然产物。姜黄就是这样一种从植物中获得的新型产品，以其多样的药用价值而闻名。在牙科领域，它在治疗牙龈和牙周疾病方面发挥着作用。
目的
评估口服姜黄凝胶治疗牙龈炎的临床疗效，并评估该凝胶的任何不良反应。
材料与方法
这项初步研究包括10名患有严重牙龈炎的个体。他们被要求使用口服姜黄凝胶21天。在此期间前后分别评估牙龈乳头出血指数（PBI）以及视觉模拟量表。对获得的数据进行统计学分析。
结果
数据采用Pearson Spearman相关系数和配对t检验进行分析。结果具有统计学意义，p<0.001。
结论
含有姜黄提取物的凝胶通过减少炎症成分，在治疗牙龈炎方面是有效的。
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