Kawashima Motoko, Uchino Miki, Yokoi Norihiko, Uchino Yuichi, Dogru Murat, Komuro Aoi, Sonomura Yukiko, Kato Hiroaki, Kinoshita Shigeru, Mimura Masaru, Tsubota Kazuo
Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan.
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
PLoS One. 2015 Apr 1;10(4):e0123299. doi: 10.1371/journal.pone.0123299. eCollection 2015.
Dry eye disease has become an important health problem. A lack of concordance between self-reported symptoms and the outcome of dry eye examinations has raised questions about dry eye disease.
To explore the association between subjective happiness and objective and subjective symptoms of dry eye disease.
The study adopted a cross-sectional design.
All the employees of a company in Osaka, Japan.
672 Japanese office workers using Visual Display Terminals (age range: 26-64 years).
The dry eye measurement tools included the Schirmer test, conjunctivocorneal staining, the tear film break-up time, as well as the administration of a dry eye symptoms questionnaire. Happiness was measured by the Subjective Happiness Scale.
Dry eye examination parameters, dry eye symptoms questionnaires, and the Subjective Happiness Scale score.
Of the 672 workers, 561 (83.5%) completed the questionnaires and examinations. The mean Subjective Happiness Scale score was 4.91 (SD = 1.01). This score was inversely correlated with the dry eye symptom score (r = -0.188, p < 0.001), but was not associated with objective findings which include conjunctivocorneal staining, low Schirmer test score, or low tear film break-up time. The level of subjective happiness was the lowest in the group without objective results, but reported subjective symptoms of dry eyes (p < 0.05).
There is evidence of the relationship between subjective happiness and self-reported symptoms of dry eyes. Findings of this study revealed a new perspective on dry eye disease, including the potential for innovative treatments of a specific population with dry eye disease.
干眼症已成为一个重要的健康问题。自我报告的症状与干眼症检查结果之间缺乏一致性引发了对干眼症的质疑。
探讨主观幸福感与干眼症客观和主观症状之间的关联。
本研究采用横断面设计。
日本大阪一家公司的所有员工。
672名使用视觉显示终端的日本上班族（年龄范围：26 - 64岁）。
干眼症测量工具包括泪液分泌试验、结膜角膜染色、泪膜破裂时间，以及干眼症症状问卷。幸福感通过主观幸福感量表进行测量。
干眼症检查参数、干眼症症状问卷以及主观幸福感量表得分。
672名员工中，561名（83.5%）完成了问卷和检查。主观幸福感量表的平均得分为4.91（标准差 = 1.01）。该得分与干眼症症状得分呈负相关（r = -0.188，p < 0.001），但与包括结膜角膜染色、泪液分泌试验低得分或泪膜破裂时间短等客观检查结果无关。在没有客观检查结果但报告有干眼主观症状的组中，主观幸福感水平最低（p < 0.05）。
有证据表明主观幸福感与自我报告的干眼症状之间存在关联。本研究结果揭示了干眼症的一个新视角，包括对特定干眼症人群进行创新治疗的潜力。
