Thorsteinsdottir Bjorg, Swetz Keith M, Albright Robert C
Department of Medicine, Division of Primary Care Internal Medicine, Biomedical Ethics Program, and Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota
Division of General Internal Medicine, Biomedical Ethics Program, and Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, Minnesota.
Clin J Am Soc Nephrol. 2015 Nov 6;10(11):2094-9. doi: 10.2215/CJN.09761014. Epub 2015 Apr 14.
Recent research highlights the potential burdens of hemodialysis for older patients with significant comorbidities, for whom there is clinical equipoise regarding the net benefits. With the advent of accountable care and bundled payment, previous incentives to offer hemodialysis to as many patients as possible are being replaced with a disincentive to dialyze high-risk patients. While this may offset the harm of overtreatment for some elderly patients, some voice concerns that the pendulum will swing too far back, with a return to ageist rationing of hemodialysis. Nephrologists should ensure that the patient's rights to be informed about the potential benefits and burdens of hemodialysis are respected, particularly because age, functional status, nutritional status, and comorbidities affect the net balance between benefits and burdens. Nephrologists are also called on to help patients make a decision, for which the patient's goals of care guide determination of potential benefit from hemodialysis. This article addresses concerns about present overtreatment and future risk of undertreatment of older adults with ESRD. It also discusses ways in which providers can ethically approach the question of initiation of hemodialysis in the elderly patient by including patient-specific estimates of prognosis, shared decision-making, and the use of specialist palliative care clinicians or ethics consultants for complex cases.
近期研究凸显了血液透析对于患有严重合并症的老年患者的潜在负担,对于这类患者,在净获益方面存在临床 equipoise。随着责任医疗和捆绑支付的出现,以往尽可能为更多患者提供血液透析的激励措施正被一种不鼓励为高风险患者进行透析的措施所取代。虽然这可能会抵消一些老年患者过度治疗的危害,但一些人担心钟摆会摆得太远,导致血液透析再次出现年龄歧视性的配给。肾病学家应确保患者了解血液透析潜在益处和负担的权利得到尊重,特别是因为年龄、功能状态、营养状况和合并症会影响益处与负担之间的净平衡。肾病学家还被要求帮助患者做出决定,为此患者的护理目标指导着对血液透析潜在益处的判定。本文探讨了对目前老年终末期肾病患者过度治疗以及未来治疗不足风险的担忧。它还讨论了医疗服务提供者在伦理上如何处理老年患者开始血液透析这一问题,包括纳入针对患者的预后估计、共同决策,以及在复杂病例中使用专科姑息治疗临床医生或伦理顾问。