Wu Jie, Yi Lina, Ni Hanzhong, Zou Lirong, Zhang Hongbin, Zeng Xianqiao, Liang Lijun, Li Laiqing, Zhong Haojie, Zhang Xin, Lin Jin-yan, Ke Changwen
Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
1] Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China [2] Guangdong Provincial Institute of Public Health, China.
Sci Rep. 2015 Jul 24;5:12507. doi: 10.1038/srep12507.
To assess the potential transmission for zoonotic influenza, sero-antibodies against two kinds of influenza viruses--classical swine H1N1 and human H1N1pdm09 virus were detected in persons whose profession involved contact with swine in Guangdong province, China. Compared to the non-exposed control group, a significantly higher proportion of subjects with occupational contact to pigs exhibited positive seroreaction against the classical H1N1 SIV. Participants aged 26-50 years were at high risk of classic swine H1N1 infections. Seropositive rate to 2009 pandemic H1N1 virus among swine workers was similar with controls. The major impact of age was apparent for younger populations. Our present study has documented evidence for swine influenza virus infection among persons with occupational swine exposures. The differences of seroreactivity for the two tested influenza subtypes emphasize the necessity of regular surveillance both in pigs and human.
为评估人感染猪流感病毒的潜在传播情况，在中国广东省，对从事与猪接触职业的人员检测了针对两种流感病毒——经典猪H1N1和人H1N1pdm09病毒的血清抗体。与未接触对照组相比，职业性接触猪的受试者中，对经典H1N1 SIV呈现阳性血清反应的比例显著更高。年龄在26至50岁的参与者感染经典猪H1N1的风险较高。养猪工人中2009年大流行H1N1病毒的血清阳性率与对照组相似。年龄的主要影响在较年轻人群中较为明显。我们目前的研究记录了职业性接触猪的人员感染猪流感病毒的证据。两种测试流感亚型血清反应性的差异强调了对猪和人类进行定期监测的必要性。
