Department of Microbiology and Immunology, Weill Cornell Medical College, 1300 New York Avenue, New York, New York 10065, USA.
Nat Rev Microbiol. 2015 Oct;13(10):651-7. doi: 10.1038/nrmicro3523.
As foundations and governments mobilize to tackle antimicrobial resistance (AMR), several experiments in academic-industrial collaboration have emerged. Here, I examine two historical precedents, the Penicillin Project and the Malaria Project of the Second World War, and two contemporary examples, the Tuberculosis Drug Accelerator programme and the Tres Cantos Open Lab. These and related experiments suggest that different strategies can be effective in managing academic-industrial collaborations, and that such joint projects can prosper in both multisite and single-site forms, depending on the specific challenges and goals of each project. The success of these strategies and the crisis of AMR warrant additional investment in similar projects.
随着基金会和政府动员起来应对抗微生物药物耐药性（AMR），一些学术-产业合作的实验已经出现。在这里，我考察了两个历史先例，即青霉素项目和第二次世界大战期间的疟疾项目，以及两个当代例子，即结核病药物加速项目和特雷斯坎托斯开放实验室。这些以及相关的实验表明，不同的策略在管理学术-产业合作方面可能是有效的，并且此类联合项目可以在多站点和单站点形式下都取得成功，具体取决于每个项目的具体挑战和目标。这些策略的成功以及 AMR 的危机需要在类似项目上进行更多投资。
