Kim Do Hyun, Han Kyungdo, Kim Soo Whan
Department of Otorhinolaryngology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Department of Biostatistics, The Catholic University of Korea, Seoul, Korea.
Allergy Asthma Immunol Res. 2016 Jan;8(1):49-54. doi: 10.4168/aair.2016.8.1.49. Epub 2015 Jul 15.
This study was conducted to evaluate the association between AR and mental health status in the general Korean adult population and to investigate the relative burden of AR on mental health using the Allergic Rhinitis and Its Impact on Asthma (ARIA) classification.
A cross-sectional study was performed by using data from 11,154 individuals, 19 years old or older in the Korean National Health and Nutrition Examination Survey 2011-2012. Univariate analysis was conducted in the healthy AR groups with weighted prevalence of demographic characteristics, socioeconomic status, and comorbid diseases. Subanalysis that classified AR severity according to the ARIA classification was carried out to evaluate the relationship of AR severity with mental health. The odds ratios (ORs) for each component representing mental health status were estimated by multiple logistic regression analysis with confounder adjustment.
Univariate analysis with the chi-square test after adjustment for age, sex, body mass index, smoking status, alcohol use status, and exercise status, components representing mental health status showed a linear relationship with the severity of AR according to the ARIA classification. Stress, depressive mood, suicidal thoughts, and psychological consultation factors were correlated with AR after adjustment for demographic characteristics and socioeconomic status. Even after adjustment for comorbid allergic diseases, the correlation remained significant with stress, depressive mood, and psychological consultation factors (OR [95% CI]; 1.227 [1.042, 1.445], 1.368 [1.095, 1.71], 1.804 [1.096, 2.969], respectively).
Patients with AR appear to be at higher risk of mental disorders in the general Korean adult population. Moreover, persistent or severe AR was correlated with poor mental health. Therefore, better control of AR may be conducive to better mental health, and more attention should be paid to the psychological status of AR patients.
本研究旨在评估韩国普通成年人群中变应性鼻炎（AR）与心理健康状况之间的关联，并使用变应性鼻炎及其对哮喘的影响（ARIA）分类法调查AR对心理健康的相对负担。
利用2011 - 2012年韩国国家健康与营养检查调查中11154名19岁及以上个体的数据进行横断面研究。对健康的AR组进行单因素分析，分析人口统计学特征、社会经济状况和合并疾病的加权患病率。根据ARIA分类对AR严重程度进行亚分析，以评估AR严重程度与心理健康的关系。通过多因素logistic回归分析并调整混杂因素，估计代表心理健康状况的各成分的比值比（OR）。
在对年龄、性别、体重指数、吸烟状况、饮酒状况和运动状况进行调整后，采用卡方检验进行单因素分析，结果显示，根据ARIA分类，代表心理健康状况的各成分与AR严重程度呈线性关系。在调整人口统计学特征和社会经济状况后，压力、抑郁情绪、自杀念头和心理咨询因素与AR相关。即使在调整合并的过敏性疾病后，压力、抑郁情绪和心理咨询因素之间的相关性仍然显著（OR [95%CI]分别为：1.227 [1.042, 1.445]、1.368 [1.095, 1.71]、1.804 [1.096, 2.969]）。
在韩国普通成年人群中，AR患者似乎患精神障碍的风险更高。此外，持续性或重度AR与心理健康不佳相关。因此，更好地控制AR可能有助于改善心理健康，应更加关注AR患者的心理状况。
