Nagao Minako, Tsugane Shoichiro
National Cancer Center Research Institute, Tokyo, Japan.
Center for Public Health Sciences, National Cancer Center, Tokyo, Japan.
Genes Environ. 2016 Jul 1;38:16. doi: 10.1186/s41021-016-0043-y. eCollection 2016.
In this article, three topics are being studied in order to understand the present state of cancer in Japan. First, the statistics on cancer mortality indicates that the mortality from cancer in young individuals has been decreasing during the last 50 years, although the total mortality from cancer has been steadily and steeply increasing. Second, epidemiological analyses of cancer causes in Japan indicated that 50 % of cancer cases are preventable, and that prevention of infection and refraining from tobacco smoking will reduce cancer mortality by about 40 %. Third, mutagenic/carcinogenic heterocyclic amines present in cooked meat/fish have been suggested to be carcinogenic in humans in many epidemiological studies carried out in Japan and other countries.
在本文中，为了解日本癌症的现状，对三个主题进行了研究。第一，癌症死亡率统计表明，尽管癌症总死亡率一直在稳步且急剧上升，但过去50年里年轻人的癌症死亡率一直在下降。第二，日本癌症病因的流行病学分析表明，50%的癌症病例是可预防的，预防感染和戒烟将使癌症死亡率降低约40%。第三，在日本和其他国家进行的许多流行病学研究表明，熟肉/鱼中存在的诱变/致癌杂环胺对人类具有致癌性。
