三氧化矿物凝聚体与洗必泰混合作为犬牙直接盖髓剂的效果：一项组织学研究。
The Effect of Mineral Trioxide Aggregate Mixed with Chlorhexidine as Direct Pulp Capping Agent in Dogs Teeth: A Histologic Study.
作者信息
Manochehrifar Hamed, Parirokh Masoud, Kakooei Sina, Oloomi Mohammad Mehdi, Asgary Saeed, Eghbal Mohammad Jafar, Mashhadi Abbas Fatemeh
机构信息
Endodontic Department, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
Oral and Dental Diseases Research Center, Dental School, Kerman University of Medical Sciences, Kerman, Iran.
出版信息
Iran Endod J. 2016 Fall;11(4):320-324. doi: 10.22037/iej.2016.12.
INTRODUCTION
The aim of the present investigation was to compare the efficacy of mineral trioxide aggregate (MTA) and 0.2% chlorhexidine (CHX) mixture to pure MTA, as a pulp capping material.
METHODS AND MATERIALS
The pulp of 24 lateral incisors and canines from four dogs were exposed and capped either with MTA or MTA+0.2% CHX. After 2 months the animals were sacrificed and the teeth were prepared for histological evaluation in terms of calcified bridge formation, the degree of inflammation and presence of necrosis. The Fisher's exact test was used for data analysis.
RESULTS
The results showed that formation of complete calcified bridge in MTA specimens was significantly more than MTA+CHX (<0.05). No significant difference was found in the degree of inflammation and necrosis between MTA and MTA+CHX groups (>0.05).
CONCLUSION
Mixing MTA with CHX as pulp capping agent had a significant negative impact on formation of calcified bridge on directly capped dog's teeth.
引言
本研究的目的是比较作为牙髓盖髓材料的三氧化矿物凝聚体（MTA）与0.2%氯己定（CHX）混合物和纯MTA的疗效。
方法和材料
从四只狗身上获取24颗侧切牙和尖牙，暴露牙髓后分别用MTA或MTA + 0.2% CHX进行盖髓。2个月后处死动物，制备牙齿用于组织学评估，评估指标包括钙化桥形成、炎症程度和坏死情况。采用Fisher精确检验进行数据分析。
结果
结果显示，MTA样本中完全钙化桥的形成明显多于MTA + CHX组（<0.05）。MTA组和MTA + CHX组之间在炎症程度和坏死方面未发现显著差异（>0.05）。
结论
将MTA与CHX混合作为牙髓盖髓剂对直接盖髓的狗牙钙化桥的形成有显著负面影响。
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