Benhamou E, Benhamou S, Auquier A, Flamant R
Département de Statistique Médicale, Institut Gustave Roussy, Villejuif, France.
Br J Cancer. 1989 Oct;60(4):601-4. doi: 10.1038/bjc.1989.322.
Data from a case-control study on lung cancer were used to evaluate how changes in cigarette habits, mainly smoking cessation, switch from non-filter to filter brands, from dark to light tobacco, or from handrolled to manufactured cigarettes, and reduction in daily consumption influence lung cancer risk. The results presented concern all males, exclusive cigarette smokers, involved in the study, i.e. 1,057 histologically confirmed lung cancer and 1,503 matched controls. The general decrease in lung cancer risk with the years since cessation was also found in each subgroup of cigarette exposure defined by duration of smoking, daily consumption and type of cigarettes smoked. Among smokers who had given up smoking from less than 10 years earlier, the lung cancer risks were two-fold higher for those who had stopped smoking for coughing or health reasons than for those who had stopped smoking for reasons other than health problems. A decrease in lung cancer risk, although not significant, was found in people who switched from non-filter brands to filter brands and from dark to light tobacco and in smokers who reduced their daily consumption of cigarettes by more than 25% as compared to smokers who had not changed habits.
一项关于肺癌的病例对照研究数据被用于评估吸烟习惯的改变如何影响肺癌风险，这些改变主要包括戒烟、从无过滤嘴香烟换成有过滤嘴香烟、从深色烟草换成浅色烟草、从手卷烟换成机制卷烟以及每日吸烟量的减少。研究结果涉及所有参与研究的男性吸烟者，即1057例经组织学确诊的肺癌患者和1503例匹配的对照者。在由吸烟持续时间、每日吸烟量和所吸香烟类型定义的每个吸烟暴露亚组中，也发现肺癌风险随戒烟年限总体呈下降趋势。在戒烟不到10年的吸烟者中，因咳嗽或健康原因戒烟者的肺癌风险是因非健康问题戒烟者的两倍。与未改变吸烟习惯的吸烟者相比，从无过滤嘴香烟换成有过滤嘴香烟、从深色烟草换成浅色烟草以及每日吸烟量减少超过25%的吸烟者，其肺癌风险有所降低，尽管降幅不显著。
