肯尼亚用于干血斑样本的2型单纯疱疹病毒血清学检测评估
Evaluation of Herpes Simplex Virus Type 2 Serological Tests for Use With Dried Blood Spots in Kenya.
作者信息
Hobbs Marcia M, Mwanyumba Sophie W, Luseno Winnie K, Hartman Shane, Halpern Carolyn T, Hallfors Denise D, Cho Hyunsan
机构信息
From the *Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC; †National HIV Reference Laboratory, Ministry of Health, Nairobi, Kenya; ‡Pacific Institute for Research and Evaluation; and §Department of Maternal and Child Health, University of North Carolina at Chapel Hill, Chapel Hill, NC.
出版信息
Sex Transm Dis. 2017 Feb;44(2):101-103. doi: 10.1097/OLQ.0000000000000557.
Abstract
We evaluated 2 assays to detect antibodies to herpes simplex virus type 2 in dried blood spots prepared from blood specimens submitted to a reference laboratory in Kenya. Dried blood spots did not perform well with the Kalon herpes simplex virus type 2 assay. Focus HerpeSelect 2 was 98.8% sensitive and 98.9% specific with dried blood spots.
摘要
我们评估了两种检测方法，用于检测从提交给肯尼亚一家参考实验室的血液标本制备的干血斑中单纯疱疹病毒2型抗体。干血斑在Kalon单纯疱疹病毒2型检测中表现不佳。Focus HerpeSelect 2对干血斑的敏感性为98.8%，特异性为98.9%。
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