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越南小规模家禽养殖场中耐多粘菌素的mcr-1基因的人畜共患病传播

Zoonotic Transmission of mcr-1 Colistin Resistance Gene from Small-Scale Poultry Farms, Vietnam.

作者信息

Trung Nguyen Vinh, Matamoros Sébastien, Carrique-Mas Juan J, Nghia Nguyen Huu, Nhung Nguyen Thi, Chieu Tran Thi Bich, Mai Ho Huynh, van Rooijen Willemien, Campbell James, Wagenaar Jaap A, Hardon Anita, Mai Nguyen Thi Nhu, Hieu Thai Quoc, Thwaites Guy, de Jong Menno D, Schultsz Constance, Hoa Ngo Thi

出版信息

Emerg Infect Dis. 2017 Mar;23(3):529-532. doi: 10.3201/eid2303.161553.

DOI:10.3201/eid2303.161553
PMID:28221105
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5382726/
Abstract

We investigated the consequences of colistin use in backyard chicken farms in Vietnam by examining the prevalence of mcr-1 in fecal samples from chickens and humans. Detection of mcr-1-carrying bacteria in chicken samples was associated with colistin use and detection in human samples with exposure to mcr-1-positive chickens.

摘要

我们通过检测鸡和人类粪便样本中mcr-1的流行情况，调查了越南后院养鸡场使用黏菌素的后果。在鸡样本中检测到携带mcr-1的细菌与黏菌素的使用有关，而在人类样本中的检测结果与接触mcr-1阳性鸡有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bf/5382726/69daeb9a1d82/16-1553-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bf/5382726/69daeb9a1d82/16-1553-F.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95bf/5382726/69daeb9a1d82/16-1553-F.jpg

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Antimicrob Agents Chemother. 2016 Oct 21;60(11):6973-6976. doi: 10.1128/AAC.01457-16. Print 2016 Nov.
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Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016.2016 年 6 月，在比利时的大肠杆菌中发现了一种新型质粒介导的粘菌素耐药基因 mcr-2。
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Transferable resistance to colistin: a new but old threat.
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Future Microbiol. 2025 Mar;20(4):287-293. doi: 10.1080/17460913.2025.2459526. Epub 2025 Jan 29.
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Genomic characterization of colistin-resistant Klebsiella pneumoniae isolated from intensive care unit patients in Egypt.埃及重症监护病房患者分离的多粘菌素耐药肺炎克雷伯菌的基因组特征。
Ann Clin Microbiol Antimicrob. 2023 Sep 9;22(1):82. doi: 10.1186/s12941-023-00632-9.
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The occurrence and molecular detection of and genes in isolated from poultry and poultry meats in Malaysia.马来西亚从家禽及禽肉中分离出的[具体物质]中[相关基因]的发生情况及分子检测
Front Microbiol. 2023 Aug 3;14:1208314. doi: 10.3389/fmicb.2023.1208314. eCollection 2023.
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