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基于迁移学习的糖尿病性黄斑水肿和干性年龄相关性黄斑变性光学相干断层扫描图像分类

Transfer learning based classification of optical coherence tomography images with diabetic macular edema and dry age-related macular degeneration.

作者信息

Karri S P K, Chakraborty Debjani, Chatterjee Jyotirmoy

机构信息

School of Medical Science and Technology, IIT Kharagpur, Kharagpur, India.

Department of Mathematics, IIT Kharagpur, Kharagpur, India.

出版信息

Biomed Opt Express. 2017 Jan 4;8(2):579-592. doi: 10.1364/BOE.8.000579. eCollection 2017 Feb 1.

DOI:10.1364/BOE.8.000579
PMID:28270969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5330546/
Abstract

We present an algorithm for identifying retinal pathologies given retinal optical coherence tomography (OCT) images. Our approach fine-tunes a pre-trained convolutional neural network (CNN), GoogLeNet, to improve its prediction capability (compared to random initialization training) and identifies salient responses during prediction to understand learned filter characteristics. We considered a data set containing subjects with diabetic macular edema, or dry age-related macular degeneration, or no pathology. The fine-tuned CNN could effectively identify pathologies in comparison to classical learning. Our algorithm aims to demonstrate that models trained on non-medical images can be fine-tuned for classifying OCT images with limited training data.

摘要

我们提出了一种用于在给定视网膜光学相干断层扫描(OCT)图像的情况下识别视网膜病变的算法。我们的方法对预训练的卷积神经网络(CNN)GoogLeNet进行微调,以提高其预测能力(与随机初始化训练相比),并在预测过程中识别显著响应,以了解学习到的滤波器特征。我们考虑了一个包含患有糖尿病性黄斑水肿、干性年龄相关性黄斑变性或无病变的受试者的数据集。与传统学习相比,微调后的CNN能够有效地识别病变。我们的算法旨在证明,在非医学图像上训练的模型可以通过有限的训练数据进行微调,以对OCT图像进行分类。

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本文引用的文献

1
Machine learning based detection of age-related macular degeneration (AMD) and diabetic macular edema (DME) from optical coherence tomography (OCT) images.基于机器学习从光学相干断层扫描(OCT)图像中检测年龄相关性黄斑变性(AMD)和糖尿病性黄斑水肿(DME)
Biomed Opt Express. 2016 Nov 3;7(12):4928-4940. doi: 10.1364/BOE.7.004928. eCollection 2016 Dec 1.
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Classification of SD-OCT Volumes Using Local Binary Patterns: Experimental Validation for DME Detection.使用局部二值模式对频域光学相干断层扫描(SD-OCT)容积进行分类:糖尿病性黄斑水肿(DME)检测的实验验证
J Ophthalmol. 2016;2016:3298606. doi: 10.1155/2016/3298606. Epub 2016 Jul 31.
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Learning layer-specific edges for segmenting retinal layers with large deformations.学习用于分割具有大变形的视网膜层的特定层边缘。
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Deep learning.深度学习。
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Kernel regression based segmentation of optical coherence tomography images with diabetic macular edema.基于核回归的糖尿病性黄斑水肿光学相干断层扫描图像分割
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Biomed Opt Express. 2014 Sep 12;5(10):3568-77. doi: 10.1364/BOE.5.003568. eCollection 2014 Oct 1.
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Probabilistic intra-retinal layer segmentation in 3-D OCT images using global shape regularization.使用全局形状正则化的 3D-OCT 图像中的概率性内视网膜层分割。
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Multiple-object geometric deformable model for segmentation of macular OCT.用于黄斑光学相干断层扫描分割的多目标几何可变形模型
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Prevalence and causes of vision loss in high-income countries and in Eastern and Central Europe: 1990-2010.高收入国家以及东欧和中欧地区视力丧失的患病率及原因:1990 - 2010年
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