Dohzono Sho, Toyoda Hiromitsu, Matsumura Akira, Terai Hidetomi, Suzuki Akinobu, Nakamura Hiroaki
Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan.
Department of Orthopaedic Surgery, Osaka City General Hospital, Osaka, Japan.
Asian Spine J. 2017 Apr;11(2):285-293. doi: 10.4184/asj.2017.11.2.285. Epub 2017 Apr 12.
A retrospective study.
To assess postoperative bone regrowth at surgical sites after lumbar decompression with >5 years of follow-up. Postoperative preservation of facet joints and segmental spinal instability following surgery were also evaluated.
Previous reports have documented bone regrowth after conventional laminectomy or laminotomy and several factors associated with new bone formation.
Forty-nine patients who underwent microscopic bilateral decompression via a unilateral approach at L4-5 were reviewed. Primary outcomes included correlations among postoperative bone regrowth, preservation of facet joints, radiographic parameters, and clinical outcomes. Secondary outcomes included comparative analyses of radiographic parameters and clinical outcomes among preoperative diagnoses (lumbar spinal stenosis, degenerative spondylolisthesis, and degenerative lumbar scoliosis).
The average value of bone regrowth at the latest follow-up was significantly higher on the dorsal side of the facet joint (3.4 mm) than on the ventral side (1.3 mm). Percent facet joint preservation was significantly smaller on the approach side (79.2%) than on the contralateral side (95.2%). Bone regrowth showed a significant inverse correlation with age, but no significant correlation was observed with facet joint preservation, gender, postoperative segmental spinal motion, or clinical outcomes. Subanalysis of these data revealed that bone regrowth at the latest follow-up was significantly greater in patients with degenerative lumbar scoliosis than in those with lumbar spinal stenosis. Postoperative segmental spinal motion at L4-L5 did not progress significantly in patients with degenerative spondylolisthesis or degenerative lumbar scoliosis compared with those with lumbar spinal stenosis.
Microscopic bilateral decompression via a unilateral approach prevents postoperative spinal instability because of satisfactory preservation of facet joints, which may be the primary reason for inadequate bone regrowth. Postoperative bone regrowth was not related to clinical outcomes and postoperative segmental spinal instability.
一项回顾性研究。
评估腰椎减压术后手术部位超过5年随访期的骨再生情况。同时评估术后小关节的保留情况以及术后节段性脊柱不稳定情况。
既往报道记录了传统椎板切除术或椎板切开术后的骨再生情况以及一些与新骨形成相关的因素。
回顾了49例行L4 - 5节段单侧入路显微镜下双侧减压术的患者。主要结局包括术后骨再生、小关节保留、影像学参数和临床结局之间的相关性。次要结局包括术前诊断(腰椎管狭窄症、退变性腰椎滑脱症和退变性腰椎侧弯症)之间影像学参数和临床结局的比较分析。
在最后一次随访时,小关节背侧的骨再生平均值(3.4毫米)显著高于腹侧(1.3毫米)。手术入路侧的小关节保留百分比(79.2%)显著低于对侧(95.2%)。骨再生与年龄呈显著负相关,但与小关节保留、性别、术后节段性脊柱活动度或临床结局无显著相关性。对这些数据的亚分析显示,退变性腰椎侧弯症患者在最后一次随访时的骨再生明显大于腰椎管狭窄症患者。与腰椎管狭窄症患者相比,退变性腰椎滑脱症或退变性腰椎侧弯症患者L4 - L5节段术后节段性脊柱活动度无显著进展。
单侧入路显微镜下双侧减压术可通过满意地保留小关节来预防术后脊柱不稳定,这可能是骨再生不足的主要原因。术后骨再生与临床结局和术后节段性脊柱不稳定无关。