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（根和茎）粗提物及其馏分的体外抗氧化和抗菌活性

In Vitro Antioxidant and Antimicrobial Activities of (Root and Stem) Crude Extract and Fractions.

作者信息

Khan Aman, Jan Gul, Khan Afsar, Gul Jan Farzana, Bahadur Ali, Danish Muhammad

机构信息

Department of Botany, Hazara University, Mansehra, Pakistan.

School of Life Science, Lanzhou University, Lanzhou, China.

出版信息

Evid Based Complement Alternat Med. 2017;2017:4040254. doi: 10.1155/2017/4040254. Epub 2017 Apr 12.

DOI:10.1155/2017/4040254
PMID:28491106
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5405573/
Abstract

The utilization of medicinal plants to treat infectious disease is a common practice in developing countries worldwide. The present study was aimed at evaluating the crude extracts of (root and stem) with different chemicals for antioxidant and antimicrobial (fungal and bacterial) potential. The results revealed that the ethyl acetate fractions of (root and stem) have significant free radical scavenging potential with values 2.96 ± 0.39 and 2.73 ± 0.84 while -butanol and aqueous fractions showed IC2.69 ± 0.26 and 3.44 ± 0.69 g/ml in stem. Furthermore, crude extract and fractions also revealed promising antibacterial activities against all tested microbial strains while aqueous fraction showed no activities against , , and . Interestingly, all crude extracts and fractions were nonactive against fungal strain, and , as compare to control. In summary, the (root and stem) extract and fraction possess antioxidant activities, which might be helpful in preventing or slowing the progress of various oxidative stresses, suggested to be a strong pharmaceutical agent.

摘要

在全球发展中国家，利用药用植物治疗传染病是一种常见的做法。本研究旨在评估（根和茎）的粗提物与不同化学物质的抗氧化和抗菌（真菌和细菌）潜力。结果表明，（根和茎）的乙酸乙酯馏分具有显著的自由基清除潜力，值分别为2.96±0.39和2.73±0.84，而丁醇馏分和水馏分在茎中的IC值分别为2.69±0.26和3.44±0.69 g/ml。此外，粗提物和馏分对所有测试的微生物菌株也显示出有前景的抗菌活性，而水馏分对、和没有活性。有趣的是，与对照相比，所有粗提物和馏分对真菌菌株和均无活性。总之，（根和茎）提取物和馏分具有抗氧化活性，这可能有助于预防或减缓各种氧化应激的进展，表明其是一种强大的药剂。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/1c74504b4523/ECAM2017-4040254.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/cdc255b2738e/ECAM2017-4040254.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/6346a8af1f7a/ECAM2017-4040254.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/1c74504b4523/ECAM2017-4040254.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/cdc255b2738e/ECAM2017-4040254.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/6346a8af1f7a/ECAM2017-4040254.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1d71/5405573/1c74504b4523/ECAM2017-4040254.003.jpg

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