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代谢综合征预防与管理的生活方式建议:一项国际专家小组建议

Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation.

作者信息

Pérez-Martínez Pablo, Mikhailidis Dimitri P, Athyros Vasilios G, Bullo Mónica, Couture Patrick, Covas María I, de Koning Lawrence, Delgado-Lista Javier, Díaz-López Andrés, Drevon Christian A, Estruch Ramón, Esposito Katherine, Fitó Montserrat, Garaulet Marta, Giugliano Dario, García-Ríos Antonio, Katsiki Niki, Kolovou Genovefa, Lamarche Benoît, Maiorino Maria Ida, Mena-Sánchez Guillermo, Muñoz-Garach Araceli, Nikolic Dragana, Ordovás José M, Pérez-Jiménez Francisco, Rizzo Manfredi, Salas-Salvadó Jordi, Schröder Helmut, Tinahones Francisco J, de la Torre Rafael, van Ommen Ben, Wopereis Suzan, Ros Emilio, López-Miranda José

机构信息

P. Pérez-Martínez, J. Delgado-Lista, A. García-Ríos, F. Pérez-Jiménez, and J. López-Miranda are with the Lipid and Atherosclerosis Unit, IMIBIC/Reina Sofia University Hospital/University of Cordoba, Cordoba, Spain. P. Pérez-Martínez, M. Bullo, M.I. Covas, J. Delgado-Lista, A. Díaz-López, R. Estruch, M. Fitó, A. García-Ríos, G. Mena-Sánchez, A. Muñoz-Garach, F. Pérez-Jiménez, J. Salas-Salvadó, F.J. Tinahones, R. de la Torre, E. Ros, and J. López-Miranda are with the CIBER Fisiopatologia Obesidad y Nutricion (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain. D.P. Mikhailidis is with the Department of Clinical Biochemistry, Royal Free Hospital Campus, University College London Medical School, University College London, London, United Kingdom. V.G. Athyros and N. Katsiki are with the Second Propedeutic Department of Internal Medicine, Medical School, Aristotle University of Thessaloniki, Hippokration Hospital, Thessaloniki, Greece. M. Bullo, A. Díaz-López, G. Mena-Sánchez, and J. Salas-Salvadó are with the Human Nutrition Unit, Biochemistry Biotechnology Department, Faculty of Medicine and Health Sciences, Hospital Universitari de Sant Joan de Reus, IISPV, Universitat Rovira i Virgili, Reus, Spain. P. Couture and B. Lamarche are with the Institute on Nutrition and Functional Foods, Laval University, Quebec, Canada. M.I. Covas, M. Fitó, and H. Schröder are with the Cardiovascular Risk and Nutrition Research Group, Hospital del Mar Research Institute, Barcelona, Spain. M.I. Covas is with the NUPROAS (Nutritional Project Assessment) Handesbolag, Nacka?, Sweden. L. de Koning is with the the Department of Pathology and Department of Laboratory Medicine, Pediatrics, and Community Health Sciences, University of Calgary, Alberta, Canada. C.A. Drevon is with the Department of Nutrition, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway. R. Estruch is with the Department of Internal Medicine, Hospital Clínic, Institut d'Investigacions Biomédiques August Pi i Sunyer, University of Barcelona, Barcelona, Spain. K. Esposito, D. Giugliano, and M. Ida Maiorino are with the Division of Endocrinology and Metabolic Diseases, Second University of Naples Diabetes Unit, Second University of Naples, Naples, Italy. M. Garaulet is with the Chronobiology Laboratory, Department of Physiology, University of Murcia and Research Biomedical Institute of Murcia, Murcia, Spain. G. Kolovou is with the 1st Cardiology Department, Onassis Cardiac Surgery Center, Athens, Greece. A. Muñoz-Garach and F.J. Tinahones are with the Servicio de Endocrinologia y Nutricion, Hospital Clinico Virgen de la Victoria, Malaga, Spain. D. Nikolic and M. Rizzo are with the Biomedical Department of Internal Medicine and Medical Specialties, University of Palermo, Palermo, Italy. J.M. Ordovás is with the Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University School of Medicine, Boston, Massachusetts, United States. J.M. Ordovás is with the Department of Epidemiology, National Center of Cardiovascular Investigations, Madrid, Spain; and the Madrid Institute of Advanced Studies-Food, Madrid, Spain. H. Schröder is with the CIBER de Epidemiologia y Salud Pública, Madrid, Spain. R. de la Torre is with the Human Pharmacology and Clinical Neurosciences Research Group, Hospital del Mar Research Institute, Barcelona, Spain. B. van Ommen and S. Wopereis are with the Toegepast Natuurwetenschappelijk Onderzoek, Zeist, The Netherlands. E. Ros is with the Lipid Clinic, Endocrinology and Nutrition Service, Institut d'Investigacions Biomédiques August Pi i Sunyer, Hospital Clínic, Barcelona, Spain.

出版信息

Nutr Rev. 2017 May 1;75(5):307-326. doi: 10.1093/nutrit/nux014.

DOI:10.1093/nutrit/nux014
PMID:28521334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5914407/
Abstract

The importance of metabolic syndrome (MetS) lies in its associated risk of cardiovascular disease and type 2 diabetes, as well as other harmful conditions such as nonalcoholic fatty liver disease. In this report, the available scientific evidence on the associations between lifestyle changes and MetS and its components is reviewed to derive recommendations for MetS prevention and management. Weight loss through an energy-restricted diet together with increased energy expenditure through physical activity contribute to the prevention and treatment of MetS. A Mediterranean-type diet, with or without energy restriction, is an effective treatment component. This dietary pattern should be built upon an increased intake of unsaturated fat, primarily from olive oil, and emphasize the consumption of legumes, cereals (whole grains), fruits, vegetables, nuts, fish, and low-fat dairy products, as well as moderate consumption of alcohol. Other dietary patterns (Dietary Approaches to Stop Hypertension, new Nordic, and vegetarian diets) have also been proposed as alternatives for preventing MetS. Quitting smoking and reducing intake of sugar-sweetened beverages and meat and meat products are mandatory. Nevertheless, there are inconsistencies and gaps in the evidence, and additional research is needed to define the most appropriate therapies for MetS. In conclusion, a healthy lifestyle is critical to prevent or delay the onset of MetS in susceptible individuals and to prevent cardiovascular disease and type 2 diabetes in those with existing MetS. The recommendations provided in this article should help patients and clinicians understand and implement the most effective approaches for lifestyle change to prevent MetS and improve cardiometabolic health.

摘要

代谢综合征(MetS)的重要性在于其与心血管疾病、2型糖尿病以及其他有害病症(如非酒精性脂肪性肝病)相关的风险。在本报告中,我们回顾了关于生活方式改变与代谢综合征及其组成部分之间关联的现有科学证据,以得出代谢综合征预防和管理的建议。通过能量限制饮食实现体重减轻,同时通过体育活动增加能量消耗,有助于代谢综合征的预防和治疗。地中海式饮食,无论是否限制能量摄入,都是一种有效的治疗方法。这种饮食模式应建立在增加不饱和脂肪摄入量(主要来自橄榄油)的基础上,并强调食用豆类、谷物(全谷物)、水果、蔬菜、坚果、鱼类和低脂乳制品,以及适量饮酒。其他饮食模式(如得舒饮食、新北欧饮食和素食饮食)也被提议作为预防代谢综合征的替代方案。戒烟以及减少含糖饮料、肉类和肉制品的摄入量是必须的。然而,证据中存在不一致和空白之处,需要更多研究来确定代谢综合征最合适的治疗方法。总之,健康的生活方式对于预防或延缓易感个体代谢综合征的发病,以及预防已有代谢综合征患者的心血管疾病和2型糖尿病至关重要。本文提供的建议应有助于患者和临床医生理解并实施最有效的生活方式改变方法,以预防代谢综合征并改善心脏代谢健康。

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