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孕期的艾滋病毒与寨卡病毒:相似情况与新挑战

HIV and ZIKA in Pregnancy: Parallel Stories and New Challenges.

作者信息

Zorrilla Carmen D, Mosquera Ana María, Rabionet Silvia, Rivera-Viñas Juana

机构信息

Obstetrics and Gynecology Department, UPR School of Medicine, Puerto Rico.

Nova Southeastern School of Pharmacy, Puerto Rico.

出版信息

Obstet Gynecol Int J. 2016;5(6). doi: 10.15406/ogij.2016.05.00180. Epub 2016 Dec 15.

Abstract

On February 1, 2016, the World Health Organization (WHO) declared the Zika virus outbreak a Public Health Emergency of International Concern (PHEIC). Because Zika virus is a relatively new infection with several transmission routes that include mosquito bites, sexual and possibly blood-related, we present the case for a parallel between the Zika epidemic and the AIDS epidemic for issues that relate particularly to pregnancy and epidemic response. We will discuss the many similarities between both epidemics while acknowledging that the viruses are different and the pathophysiology and disease manifestation are also different. What can we learn of the three decades of awareness campaigns, community involvement, clinical, behavior and prevention research, activism and policy-making related to HIV/AIDS? How can the lessons and experience of dealing with the HIV epidemic can help us deal with the ongoing Zika epidemic? Is there a roadmap that we can follow? Our position is that we can and we should. Parallels between the Zika and HIV/AIDS epidemics particularly in relation to pregnancy can be established. Lessons and successes from the HIV/AIDS epidemic control efforts can guide us towards comprehensive approaches to improve the health of women and infants at risk for Zika.

摘要

2016年2月1日,世界卫生组织(WHO)宣布寨卡病毒疫情构成国际关注的突发公共卫生事件(PHEIC)。由于寨卡病毒是一种相对较新的传染病,其传播途径包括蚊虫叮咬、性传播以及可能的血液传播,我们将阐述寨卡疫情与艾滋病疫情在一些特别与妊娠及疫情应对相关的问题上的相似之处。我们将探讨这两种疫情之间的诸多相似之处,同时承认这两种病毒不同,其病理生理学及疾病表现也各异。我们能从与艾滋病毒/艾滋病相关的长达三十年的宣传活动、社区参与、临床、行为及预防研究、维权行动和政策制定中学到什么?应对艾滋疫情的经验教训如何能帮助我们应对当前的寨卡疫情?是否有我们可以遵循的路线图?我们的立场是我们能够且应该这样做。寨卡疫情与艾滋病毒/艾滋病疫情之间,尤其是在与妊娠相关方面,可以找到相似之处。艾滋病毒/艾滋病疫情防控工作的经验教训和成功案例能够引导我们采取综合措施,改善面临寨卡病毒风险的妇女和婴儿的健康状况。

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