Centre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, College of Medical, Veterinary and Life Sciences, Joseph Black Building, University of Glasgow, Glasgow, Scotland, UK.
Biomedical Engineering Research Division, University of Glasgow, Glasgow, Scotland, UK.
Nanomedicine. 2018 Oct;14(7):2455-2464. doi: 10.1016/j.nano.2017.03.020. Epub 2017 May 26.
Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the field of biomaterials research. In this review, we discuss relevant nanofabrication techniques and how they are combined with bioengineering applications to mimic the natural extracellular matrix (ECM) and create valuable nanoscale interfaces.
近年来，细胞对纳米级特征的反应行为调控一直是研究的重点，而成功制备能够模拟天然纳米级界面的纳米级特征在生物材料研究领域引起了极大的关注。在这篇综述中，我们讨论了相关的纳米制造技术，以及它们如何与生物工程应用相结合，以模拟天然细胞外基质（ECM）并创建有价值的纳米级界面。
