定量蛋白质组学：基础和应用研究中的挑战和机遇。
Quantitative proteomics: challenges and opportunities in basic and applied research.
机构信息
Department of Human Genetics, University of California, Los Angeles, Los Angeles, California, USA.
Department of Genetics, Stanford University, Stanford, California, USA.
出版信息
Nat Protoc. 2017 Jul;12(7):1289-1294. doi: 10.1038/nprot.2017.040. Epub 2017 Jun 1.
PMID:28569762
Abstract
In this Perspective, we discuss developments in mass-spectrometry-based proteomic technology over the past decade from the viewpoint of our laboratory. We also reflect on existing challenges and limitations, and explore the current and future roles of quantitative proteomics in molecular systems biology, clinical research and personalized medicine.
摘要
在本观点中，我们从实验室的角度讨论了过去十年中基于质谱的蛋白质组学技术的发展。我们还反思了现有的挑战和局限性，并探讨了定量蛋白质组学在分子系统生物学、临床研究和个性化医学中的当前和未来作用。
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