Frank J W, Mai V
Lancet. 1985 Sep 21;2(8456):654-7. doi: 10.1016/s0140-6736(85)90014-5.
It is argued that women who find asymptomatic benign breast lesions by breast self-examination (BSE) are exposed to unnecessary anxiety, unnecessary medical investigations (including invasive procedures), and potential risks of false reassurance. "False positives" so greatly outnumber patient-detected cancers below age 30 to 35 that the potential for net benefit from BSE in this age group is remote. BSE in younger women, by encouraging invasive and costly medical investigation of many asymptomatic benign breast lumps needing no treatment, could well do more harm than good.
有人认为,通过乳房自我检查(BSE)发现无症状良性乳腺病变的女性会面临不必要的焦虑、不必要的医学检查(包括侵入性检查)以及错误安慰的潜在风险。在30至35岁以下的人群中,“假阳性”的数量远远超过患者自行检测出的癌症数量,以至于在这个年龄段,BSE带来净益处的可能性微乎其微。对于年轻女性而言,BSE会促使对许多无需治疗的无症状良性乳腺肿块进行侵入性且昂贵的医学检查,这很可能弊大于利。