Jayaraj Ravindran, Megha Pankajshan, Sreedev Puthur
Division of Forest Ecology and Biodiversity Conservation, Kerala Forest Research Institute, Thrissur, Kerala, India.
Interdiscip Toxicol. 2016 Dec;9(3-4):90-100. doi: 10.1515/intox-2016-0012. Epub 2017 May 17.
Organochlorine (OC) pesticides are synthetic pesticides widely used all over the world. They belong to the group of chlorinated hydrocarbon derivatives, which have vast application in the chemical industry and in agriculture. These compounds are known for their high toxicity, slow degradation and bioaccumulation. Even though many of the compounds which belong to OC were banned in developed countries, the use of these agents has been rising. This concerns particularly abuse of these chemicals which is in practice across the continents. Though pesticides have been developed with the concept of target organism toxicity, often non-target species are affected badly by their application. The purpose of this review is to list the major classes of pesticides, to understand organochlorine pesticides based on their activity and persistence, and also to understand their biochemical toxicity.
有机氯农药是全世界广泛使用的合成农药。它们属于氯代烃衍生物类别,在化学工业和农业中有着广泛应用。这些化合物以其高毒性、缓慢降解和生物累积性而闻名。尽管许多属于有机氯的化合物在发达国家已被禁用,但这些药剂的使用仍在增加。这尤其涉及到这些化学品在各大洲的实际滥用情况。尽管农药的研发是基于目标生物毒性的概念,但它们的应用往往会对非目标物种造成严重影响。本综述的目的是列出主要的农药类别,基于其活性和持久性了解有机氯农药,并了解它们的生化毒性。