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韩国近期高致病性禽流感病毒的爆发。

Recent outbreaks of highly pathogenic avian influenza viruses in South Korea.

作者信息

Kim Hye Kwon, Jeong Dae Gwin, Yoon Sun-Woo

机构信息

Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Korea.

University of Science and Technology (UST), Daejeon, Korea.

出版信息

Clin Exp Vaccine Res. 2017 Jul;6(2):95-103. doi: 10.7774/cevr.2017.6.2.95. Epub 2017 Jul 26.

DOI:10.7774/cevr.2017.6.2.95
PMID:28775973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5540969/
Abstract

Outbreaks of H5 highly pathogenic avian influenza viruses (HPAIVs) have caused economic loss for the poultry industry and posed a threat to public health. In South Korea, novel reassortants of HPAIVs such as H5N6 and H5N8 had been circulating in poultry. Here, we will discuss the identity of recent novel reassortants of Korean H5 HPAIVs and the recent advances in vaccine development, which will be useful for controlling HPAIV transmission in poultry and for effectively preventing future epidemics and pandemics.

摘要

H5高致病性禽流感病毒（HPAIV）的暴发给家禽业造成了经济损失，并对公众健康构成了威胁。在韩国，H5N6和H5N8等新型HPAIV重配株一直在家禽中传播。在此，我们将讨论韩国H5 HPAIV近期新型重配株的特性以及疫苗开发的最新进展，这将有助于控制HPAIV在家禽中的传播，并有效预防未来的疫情和大流行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95a0/5540969/86b49576cf6f/cevr-6-95-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95a0/5540969/86b49576cf6f/cevr-6-95-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95a0/5540969/86b49576cf6f/cevr-6-95-g001.jpg

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Preliminary Epidemiologic Assessment of Human Infections With Highly Pathogenic Avian Influenza A(H5N6) Virus, China.中国高致病性甲型禽流感（H5N6）病毒人间感染的初步流行病学评估
Clin Infect Dis. 2017 Aug 1;65(3):383-388. doi: 10.1093/cid/cix334.
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Evolution of H5 highly pathogenic avian influenza: sequence data indicate stepwise changes in the cleavage site.H5高致病性禽流感的演变：序列数据表明裂解位点存在逐步变化。
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Identification of Two novel reassortant avian influenza a (H5N6) viruses in whooper swans in Korea, 2016.
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Viruses. 2020 Sep 7;12(9):993. doi: 10.3390/v12090993.
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Viruses. 2020 Jan 15;12(1):100. doi: 10.3390/v12010100.
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