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中国东部老年人群近视的患病率及危险因素

Prevalence and risk factors for myopia in older adult east Chinese population.

作者信息

Xu Cailian, Pan Chenwei, Zhao Chunhua, Bi Mingchao, Ma Qinghua, Cheng Jianhui, Song E

机构信息

The First Hospital of Jilin University, NO.71 Xinmin Street, Changchun, China.

Lixiang Eye Hospital of Soochow University, NO.200 Ganjiang Eastern Road, Suzhou, China.

出版信息

BMC Ophthalmol. 2017 Oct 13;17(1):191. doi: 10.1186/s12886-017-0574-4.

Abstract

BACKGROUND

To determine the prevalence and associated factors for myopia and high myopia among older population in a rural community in Eastern China.

METHODS

A community-based, cross-sectional survey was conducted in the Weitang town located in Suzhou, an urban metropolis in East China. A total of 5613 Chinese residents aged 60 years and older were invited to complete a questionnaire and participated in a detailed eye examination,including measurements of visual acuity and refractive error using autorefraction and subjective refraction. Myopia and high myopia was defined as SE < -0.5 diopters (D) and < -5.0 D, respectively.

RESULTS

Among the 5613 participating individuals, 4795 (85.4%) complete refraction data of phakic right eye was included for analysis. The age-adjusted prevalence was 21.1% (95% confidence interval [CI], 19.9-22.2) for myopia and 2.5% (95% CI, 2.1-2.9) for high myopia. The prevalence of myopia tended to increase significantly with age(p < 0.001),and women had a higher rate of myopia than men (p < 0.001). According to multivariate logistic regression analysis, adults who were older (odds ration[OR]:1.05; 95% CI:1.04-1.07), spent more time for sleeping at night (OR:1.12;95% CI: 1.06-1.18),or had cataract (OR:1.60;95% CI:1.36-1.88) and family history of myopia (OR:1.47;95% CI:1.23-1.77), are more susceptible to myopia (p < 0.001). People who had older age, family history, cataract and specially longer night-time sleep duration, would have a higher risk of myopia.

CONCLUSION

Myopia and high myopia among rural old adult population in Eastern China presents common. The current literature unanticipated suggests that there was a positive significant association between prevalence of myopia and night-time sleep duration among adult. Our data provide some evidence of this relationship and highlight the need for larger studies to further investigate this relationship longitudinally and explore mechanism therein.

摘要

背景

确定中国东部农村社区老年人群中近视和高度近视的患病率及相关因素。

方法

在中国东部城市苏州的渭塘镇进行了一项基于社区的横断面调查。共邀请了5613名60岁及以上的中国居民完成问卷调查,并参加详细的眼部检查,包括使用自动验光和主观验光测量视力和屈光不正。近视和高度近视分别定义为等效球镜(SE)<-0.5屈光度(D)和<-5.0D。

结果

在5613名参与个体中,纳入4795名(85.4%)有晶状体右眼的完整验光数据进行分析。年龄调整后的近视患病率为21.1%(95%置信区间[CI],19.9 - 22.2),高度近视为2.5%(95%CI,2.1 - 2.9)。近视患病率随年龄显著增加(p<0.001),女性近视率高于男性(p<0.001)。根据多因素logistic回归分析,年龄较大的成年人(比值比[OR]:1.05;95%CI:1.04 - 1.07)、夜间睡眠时间较长(OR:1.12;95%CI:1.06 - 1.18)、患有白内障(OR:1.60;95%CI:1.36 - 1.88)以及有近视家族史(OR:1.47;95%CI:1.23 - 1.77)者更易患近视(p<0.001)。年龄较大、有家族史、患白内障且夜间睡眠时间特别长的人患近视风险更高。

结论

中国东部农村老年人群中近视和高度近视较为常见。当前文献意外提示成年人近视患病率与夜间睡眠时间之间存在显著正相关。我们的数据为这种关系提供了一些证据,并强调需要进行更大规模的研究以进一步纵向研究这种关系并探索其中机制。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad8a/5640960/afc93f714d4e/12886_2017_574_Fig1_HTML.jpg

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