Department of Nutrition, Aerospace Center Hospital, Beijing, 100049, P. R. China.
Department of Laboratorial Science and Technology, School of Public Health, Peking University, Beijing, 100191, P. R. China.
Sci Rep. 2017 Oct 18;7(1):13434. doi: 10.1038/s41598-017-13955-3.
The role of Helicobacter pylori (H. pylori) infection in haematological system diseases is not well understood. We conducted this retrospective study to explore the association between H. pylori infection and anaemia in the Chinese population. This retrospective study was performed in Aerospace Center Hospital in Beijing. We derived the data from the registration system of the physical population between 2012-2016. Logistic regression models were used to explore the association between H. pylori infection and anaemia. Among 17,791 subjects, there were 7,804 (43.9%) subjects with H. pylori infection and 950 (5.3%) with anaemia. The prevalence of anaemia in the H. pylori (+) group was significantly higher than in the H. pylori (-) group after adjusting for age, sex, marriage, underlying diseases and body mass index. Compared to H. pylori (-), the OR of H. pylori (+) was 1.39 for moderate-to-severe anaemia and 1.05 for mild anaemia. The level of haemoglobin was lower in the H. pylori (+) group than in the H. pylori (-) group. This study indicates that H. pylori infection may be related to anaemia and haemoglobin level in the Chinese population.
幽门螺杆菌（H. pylori）感染在血液系统疾病中的作用尚不清楚。我们进行了这项回顾性研究，以探讨在中国人群中幽门螺杆菌感染与贫血之间的关系。这项回顾性研究在北京航天中心医院进行。我们从 2012-2016 年的人口登记系统中提取数据。使用逻辑回归模型探讨幽门螺杆菌感染与贫血之间的关系。在 17791 名受试者中，有 7804 名（43.9%）受试者感染了幽门螺杆菌，950 名（5.3%）患有贫血。在调整年龄、性别、婚姻状况、基础疾病和体重指数后，幽门螺杆菌（+）组贫血的患病率明显高于幽门螺杆菌（-）组。与幽门螺杆菌（-）相比，幽门螺杆菌（+）的中度至重度贫血和轻度贫血的比值比分别为 1.39 和 1.05。幽门螺杆菌（+）组的血红蛋白水平低于幽门螺杆菌（-）组。本研究表明，幽门螺杆菌感染可能与中国人群的贫血和血红蛋白水平有关。
