Suppr超能文献

紫外线照射对钛合金与骨组织骨结合的影响。

Effect of Ultraviolet Irradiation on the Osseointegration of a Titanium Alloy with Bone.

作者信息

Yadav Ashish, Yadav Ranjana, Gupta Aratee, Baranwal Akash, Bhatnagar Atul, Singh Vakil

机构信息

Department of Dental Surgery, Government Medical College, Azamgarh, India.

Department of Public Health Dentistry, Babu Banarasi Das College of Dental Sciences, Lucknow, India.

出版信息

Contemp Clin Dent. 2017 Oct-Dec;8(4):571-578. doi: 10.4103/ccd.ccd_576_17.

Abstract

INTRODUCTION

Attempt has been made to analyze the potential of titanium (Ti) alloy for osteointegration by the effect of surface photo functionalization in different aspects as follows: in Ringer's solution, cell growth, and study on rabbit. The present study was aimed to investigate the influence of ultraviolet (UV) light on surface topography, corrosion behavior, and bioactivity of indigenously manufactured samples of Ti alloy mini-implant.

MATERIALS AND METHODS

The study includes surface modification of Ti samples by UV treatment, corrosion testing of the specimens using Potentiostat (GAMRY System), qualitative examination of modified surface topography using scanning electron microscope, and cellular viability test on Ti alloy surface (3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide ASSAY). To find the effect of UV light on implant bone integration, biochemical test was performed on the femur of rabbits.

RESULTS AND DISCUSSION

Corrosion resistance of untreated Ti alloy in Ringer's solution was found to be less, whereas corrosion rate was more. Corrosion resistance of UV-treated samples was found to increase significantly, thereby lowering the corrosion rate. Cell growth in UV-treated specimen was observed to be higher than that in untreated samples. It is important to mention that cell growth was significantly enhanced on samples which were UV treated for longer duration of time.

CONCLUSIONS

There was a marked improvement in cell growth on UV-treated Ti alloy samples. Hence, it is expected that it would enhance the process of osseointegration of Ti with bone. Another important finding obtained was that the removal torque values of UV-treated implants were higher than that of untreated implants. The overall result reveals that UV treatment of implants does help us in speeding up the osseointegration process.

摘要

引言

已尝试通过以下不同方面的表面光功能化效应来分析钛(Ti)合金的骨整合潜力:在林格氏溶液中、细胞生长以及在兔子身上进行研究。本研究旨在探讨紫外线(UV)对国产Ti合金微型种植体样品的表面形貌、腐蚀行为和生物活性的影响。

材料与方法

该研究包括通过紫外线处理对Ti样品进行表面改性,使用恒电位仪(GAMRY系统)对样品进行腐蚀测试,使用扫描电子显微镜对改性表面形貌进行定性检查,以及对Ti合金表面进行细胞活力测试(3-(4,5-二甲基噻唑-2-基)-2,5-二苯基四氮唑溴盐测定法)。为了研究紫外线对种植体骨整合的影响,对兔子的股骨进行了生化测试。

结果与讨论

发现未处理的Ti合金在林格氏溶液中的耐腐蚀性较低,而腐蚀速率较高。发现经紫外线处理的样品的耐腐蚀性显著提高,从而降低了腐蚀速率。观察到经紫外线处理的样品中的细胞生长高于未处理的样品。需要指出的是,在经过较长时间紫外线处理的样品上,细胞生长显著增强。

结论

经紫外线处理的Ti合金样品上的细胞生长有显著改善。因此,预计它将增强Ti与骨的骨整合过程。另一个重要发现是,经紫外线处理的种植体的去除扭矩值高于未处理的种植体。总体结果表明,对种植体进行紫外线处理确实有助于我们加快骨整合过程。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7306/5754978/fa436128d896/CCD-8-571-g002.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验