Department of Clinical Psychology und Psychotherapy, University of Tübingen, Tübingen, Germany.
Department of Psychiatry and Psychotherapy, Neurophysiology and Interventional Neuropsychiatry, University of Tübingen, Tübingen, Germany.
Eur Arch Psychiatry Clin Neurosci. 2019 Sep;269(6):731-740. doi: 10.1007/s00406-018-0878-2. Epub 2018 Feb 3.
Antisocial personality disorder is characterized by a stable, lifelong pattern of disregard for and violation of others' rights. Disruptions in the representation of fairness norms may represent a key mechanism in the development and maintenance of this disorder. Here, we investigated fairness norm considerations and reactions to their violations. To examine electrophysiological correlates, we assessed the medial frontal negativity (MFN), an event-related potential previously linked to violations of social expectancy and norms. Incarcerated antisocial violent offenders (AVOs, n = 25) and healthy controls (CTLs, n = 24) acted as proposers in the dictator game (DG) and ultimatum game (UG) and received fair vs. unfair UG offers from either another human (social context) or a computer (non-social context). Results showed that AVOs made lower offers in the DG but not the UG, indicating more rational and strategic behavior. Most importantly, when acting as recipients in the UG, acceptance rates were modulated by social context in CTLs, while AVOs generally accepted more offers. Correspondingly, ERP data indicated pronounced MFN amplitudes following human offers in CTLs, whereas MFN amplitudes in AVOs were generally reduced. The current data suggest intact fairness norm representations but altered reactions to their violation in antisocial personality disorder.
反社会人格障碍的特征是对他人权利的长期稳定漠视和侵犯。公平规范表现的中断可能代表着这种障碍发展和维持的一个关键机制。在这里，我们研究了公平规范的考虑因素以及对其违反的反应。为了研究电生理相关性，我们评估了内侧前额负波（MFN），这是一种与违反社会期望和规范相关的事件相关电位。被监禁的反社会暴力罪犯（AVOs，n=25）和健康对照组（CTLs，n=24）在独裁者游戏（DG）和最后通牒游戏（UG）中担任提议者，并从另一个人（社会情境）或计算机（非社会情境）收到公平或不公平的 UG 报价。结果表明，AVOs 在 DG 中的报价较低，但在 UG 中则没有，这表明他们的行为更具理性和策略性。最重要的是，当作为 UG 的接受者时，CTL 中的接受率受社会情境的调节，而 AVOs 通常接受更多的报价。相应地，ERP 数据表明，在 CTLs 中，在收到人类报价后，MFN 振幅明显增加，而在 AVOs 中，MFN 振幅通常会降低。目前的数据表明，反社会人格障碍患者的公平规范表现完整，但对其违反的反应发生改变。
