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骨科中的纳米技术:一项以临床为导向的综述。

Nanotechnology in orthopedics: a clinically oriented review.

作者信息

Smith Walter Ryan, Hudson Parke William, Ponce Brent Andrew, Rajaram Manoharan Sakthivel Rajan

机构信息

Department of Orthopaedic Surgery, University of Alabama at Birmingham, 1313 13 St. South, Birmingham, AL, 35205, USA.

Department of Orthopaedic Surgery, University of Alabama at Birmingham, FOT 950, 20 Street South, Birmingham, AL, 35294, USA.

出版信息

BMC Musculoskelet Disord. 2018 Mar 2;19(1):67. doi: 10.1186/s12891-018-1990-1.

Abstract

The utility of nanotechnology in medicine, specifically within the field of orthopedics, is a topic of extensive research. Our review provides a unique comprehensive overview of the current and potential future uses of nanotechnology with respect to orthopedic sub-specialties. Nanotechnology offers an immense assortment of novel applications, most notably the use of nanomaterials as scaffolds to induce a more favorable interaction between orthopedic implants and native bone. Nanotechnology has the capability to revolutionize the diagnostics and treatment of orthopedic surgery, however the long-term health effects of nanomaterials are poorly understood and extensive research is needed regarding clinical safety.

摘要

纳米技术在医学领域,特别是在骨科领域的应用,是一个广泛研究的课题。我们的综述对纳米技术在骨科各亚专业的当前及潜在未来应用提供了独特而全面的概述。纳米技术提供了大量新颖的应用,最显著的是使用纳米材料作为支架,以诱导骨科植入物与天然骨之间产生更有利的相互作用。纳米技术有能力彻底改变骨科手术的诊断和治疗,然而,纳米材料对健康的长期影响了解甚少,需要就临床安全性进行广泛研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32d5/5833027/4ce6c929c1b9/12891_2018_1990_Fig1_HTML.jpg

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