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Smart cancer therapy with DNA origami.

作者信息

Tasciotti Ennio

机构信息

Center for Biomimetic Medicine and Center for Musculoskeletal Regeneration, Houston Methodist Orthopedic and Sports Medicine, Houston Methodist Hospital, Houston Methodist Research Institute, Houston, Texas, USA.

出版信息

Nat Biotechnol. 2018 Mar 6;36(3):234-235. doi: 10.1038/nbt.4095.

DOI:10.1038/nbt.4095
PMID:29509744
Abstract
摘要

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A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo.一种 DNA 纳米机器人在体内对分子触发做出反应，从而起到癌症治疗的作用。
Nat Biotechnol. 2018 Mar;36(3):258-264. doi: 10.1038/nbt.4071. Epub 2018 Feb 12.
2
Biotechnological mass production of DNA origami.生物技术大规模生产 DNA 折纸。
Nature. 2017 Dec 6;552(7683):84-87. doi: 10.1038/nature24650.
3
Bio-inspired engineering of cell- and virus-like nanoparticles for drug delivery.仿生工程化的细胞和病毒样纳米颗粒用于药物递送。
DNA 纳米结构的机械和结构特性的相互作用决定了它们与脂质膜的静电相互作用。
Nanoscale. 2023 Feb 9;15(6):2849-2859. doi: 10.1039/d2nr05368c.
4
Innovations in Disease State Responsive Soft Materials for Targeting Extracellular Stimuli Associated with Cancer, Cardiovascular Disease, Diabetes, and Beyond.针对与癌症、心血管疾病、糖尿病等相关的细胞外刺激的疾病状态响应型软材料的创新。
Adv Mater. 2021 Nov;33(46):e2007504. doi: 10.1002/adma.202007504. Epub 2021 Jun 17.
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An efficient enzyme-triggered controlled release system for colon-targeted oral delivery to combat dextran sodium sulfate (DSS)-induced colitis in mice.一种高效的酶触发控制释放系统，用于结肠靶向口服递药，以治疗小鼠葡聚糖硫酸钠（DSS）诱导的结肠炎。
Drug Deliv. 2021 Dec;28(1):1120-1131. doi: 10.1080/10717544.2021.1934189.
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Accessing and Assessing the Cell-Surface Glycocalyx Using DNA Origami.利用 DNA 折纸术获取和评估细胞表面糖萼。
Nano Lett. 2021 Jun 9;21(11):4765-4773. doi: 10.1021/acs.nanolett.1c01236. Epub 2021 May 24.
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An Effective Multi-Stage Liposomal DNA Origami Nanosystem for In Vivo Cancer Therapy.一种用于体内癌症治疗的高效多阶段脂质体DNA折纸纳米系统。
Cancers (Basel). 2019 Dec 12;11(12):1997. doi: 10.3390/cancers11121997.
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Recent Progress in the Development of Poly(lactic--glycolic acid)-Based Nanostructures for Cancer Imaging and Therapy.用于癌症成像与治疗的聚乳酸-乙醇酸纳米结构研发的最新进展
Pharmaceutics. 2019 Jun 14;11(6):280. doi: 10.3390/pharmaceutics11060280.
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