基于有机分子的光热剂：不断扩展的光热治疗领域
Organic molecule-based photothermal agents: an expanding photothermal therapy universe.
作者信息
Jung Hyo Sung, Verwilst Peter, Sharma Amit, Shin Jinwoo, Sessler Jonathan L, Kim Jong Seung
机构信息
Department of Chemistry, Korea University, Seoul 02841, Korea.
出版信息
Chem Soc Rev. 2018 Apr 3;47(7):2280-2297. doi: 10.1039/c7cs00522a.
Abstract
Over the last decade, organic photothermal therapy (PTT) agents have attracted increasing attention as a potential complement for, or alternative to, classical drugs and sensitizers involving inorganic nanomaterials. In this tutorial review, we provide a structured description of the main classes of organic photothermal agents and their characteristics. Representative agents that have been studied in the context of photothermal therapy since 2000 are summarized and recent advances in using PTT agents to address various cancers indications are highlighted.
摘要
在过去十年中，有机光热疗法（PTT）试剂作为传统药物和涉及无机纳米材料的敏化剂的潜在补充或替代品，受到了越来越多的关注。在本教程综述中，我们对主要类别的有机光热剂及其特性进行了结构化描述。总结了自2000年以来在光热疗法背景下研究的代表性试剂，并强调了使用PTT试剂治疗各种癌症适应症的最新进展。
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