Ghanbari-Niaki Abbass, Saeidi Ayoub, Ahmadian Mehdi, Gharahcholo Leila, Naghavi Nooshin, Fazelzadeh Mohammad, Mahjoub Soleiman, Myers Stephen, Williams Andrew
Exercise Biochemistry Division, Faculty of Physical Education and Sport Science, University of Mazandaran, Babolsar, Iran.
Department of Physical Education and Sport Sciences, Aliabad Katoul Branch, Islamic Azad University, Aliabad Katoul, Iran.
Integr Med Res. 2018 Mar;7(1):44-52. doi: 10.1016/j.imr.2018.01.007. Epub 2018 Jan 31.
We examined the effect of antioxidant supplementation and exercise on irisin within postmenopausal women.
Forty-eight participants (age: 55.7 ± 4.9 years; weight: 68.0 ± 6.3 kg; BMI 27.0 ± 2.7; mean ± SD) were randomized into four groups for the eight week intervention: control group (CG; = 12), resistance training group (RTG; = 12), supplementation with group (ZG; = 12), or supplementation with and resistance training group (ZRTG; = 12). RTG and ZRTG performed circuit resistance training, and both ZG and ZRTG consumed 500 mg of every day during the intervention. Blood samples were taken 48 hours before and after the intervention.
There was a significant difference in irisin at post-training, with greater levels in ZRTG compared to CG. A significant increase was noted for irisin at post-training compared to pre-training for ZG, RTG, and ZRTG. Moreover, we identified a significant decrease in malondialdehyde in the RTG and ZRTG groups and increase in glutathione in the ZG, RTG, and ZRTG groups when compared to CG.
These findings showed that exercise, supplementation or their combination led to an increase in irisin.
我们研究了补充抗氧化剂和运动对绝经后女性鸢尾素的影响。
48名参与者（年龄：55.7±4.9岁；体重：68.0±6.3千克；体重指数27.0±2.7；均值±标准差）被随机分为四组，进行为期八周的干预：对照组（CG；n = 12）、阻力训练组（RTG；n = 12）、补充[具体物质]组（ZG；n = 12）或补充[具体物质]与阻力训练组（ZRTG；n = 12）。RTG和ZRTG进行循环阻力训练，在干预期间，ZG和ZRTG每天都摄入500毫克[具体物质]。在干预前后48小时采集血样。
训练后鸢尾素水平存在显著差异，与CG相比，ZRTG中的水平更高。与训练前相比，ZG、RTG和ZRTG在训练后的鸢尾素水平显著升高。此外，与CG相比，我们发现RTG组和ZRTG组中的丙二醛显著降低，ZG组、RTG组和ZRTG组中的谷胱甘肽增加。
这些发现表明，运动、补充[具体物质]或它们的组合导致鸢尾素增加。
