Central Laboratory, Peking University Hospital of Stomatology, Beijing, 100081, China.
Department of Orthodontics, Peking University Hospital of Stomatology, Beijing, 100081, China.
Protein Cell. 2018 May;9(5):488-500. doi: 10.1007/s13238-018-0548-1. Epub 2018 May 7.
Microbes appear in every corner of human life, and microbes affect every aspect of human life. The human oral cavity contains a number of different habitats. Synergy and interaction of variable oral microorganisms help human body against invasion of undesirable stimulation outside. However, imbalance of microbial flora contributes to oral diseases and systemic diseases. Oral microbiomes play an important role in the human microbial community and human health. The use of recently developed molecular methods has greatly expanded our knowledge of the composition and function of the oral microbiome in health and disease. Studies in oral microbiomes and their interactions with microbiomes in variable body sites and variable health condition are critical in our cognition of our body and how to make effect on human health improvement.
微生物存在于人类生活的每一个角落,影响着人类生活的方方面面。人类口腔包含了许多不同的栖息地。口腔中可变微生物的协同作用和相互作用有助于人体抵御外来不良刺激的侵袭。然而,微生物菌群的失衡会导致口腔疾病和全身性疾病。口腔微生物组在人类微生物群落和人类健康中发挥着重要作用。最近开发的分子方法的使用极大地扩展了我们对健康和疾病中口腔微生物组的组成和功能的认识。对口腔微生物组及其与不同身体部位和不同健康状况的微生物组相互作用的研究,对于我们认识我们的身体以及如何改善人类健康具有重要意义。