OptoBase：用于分子光遗传学的网络平台。

OptoBase: A Web Platform for Molecular Optogenetics.

作者信息

Kolar Katja, Knobloch Christian, Stork Hendrik, Žnidarič Matej, Weber Wilfried

机构信息

Faculty of Biology , University of Freiburg , 79104 Freiburg , Germany.

BIOSS - Centre for Biological Signalling Studies , University of Freiburg , 79104 Freiburg , Germany.

出版信息

ACS Synth Biol. 2018 Jul 20;7(7):1825-1828. doi: 10.1021/acssynbio.8b00120. Epub 2018 Jul 3.

DOI:10.1021/acssynbio.8b00120

PMID:29913065

Abstract

OptoBase is an online platform for molecular optogenetics. At its core is a hand-annotated and ontology-supported database that aims to cover all existing optogenetic switches and publications, which is further complemented with a collection of convenient optogenetics-related web tools. OptoBase is meant both for expert optogeneticists to easily keep track of the field, as well as for all researchers who find optogenetics inviting as a powerful tool to address their biological questions of interest. It is available at https://www.optobase.org . This work also presents OptoBase-based analysis of the trends in molecular optogenetics.

摘要

OptoBase是一个用于分子光遗传学的在线平台。其核心是一个经过人工注释且有本体支持的数据库，旨在涵盖所有现有的光遗传学开关和出版物，并辅以一系列便捷的光遗传学相关网络工具。OptoBase既供光遗传学专家轻松跟踪该领域的进展，也供所有认为光遗传学是解决其感兴趣的生物学问题的有力工具而对其感兴趣的研究人员使用。可通过https://www.optobase.org访问该平台。这项工作还展示了基于OptoBase对分子光遗传学趋势的分析。