Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Department of Hematology, Nanlou Division & National Clinical Research Center for Geriatric Disease, Chinese PLA General Hospital, Beijing, China.
Ann Fam Med. 2018 Sep;16(5):408-418. doi: 10.1370/afm.2292.
Our purpose was to investigate the relationship between intake of excess free fructose beverages and allergy among children and adolescents.
We analyzed data of 860 children (aged 6 to 12 years) and 1,142 adolescents (aged 13 to 19 years) from the National Health and Nutrition Examination Survey 2005-2006. Logistic regression analyses were performed to determine the associations between consumption of excess free fructose beverages and allergic symptoms or allergic sensitization.
The pattern of findings was not entirely consistent, but some analyses supported the hypothesis of an association between intake of excess free fructose beverages and allergy. After controlling for the potential confounders, children who consumed nondiet fruit drinks at least 5 times per week had a nearly 2.5-fold greater odds of allergic sensitization than did those who consumed such drinks only 1 to 3 times per month (OR = 2.446; 95% CI, 1.583-3.780). Adolescents who consumed excess free fructose beverages at least 5 times per week or 1 to 4 times per week had about fivefold greater odds of presence of allergic symptoms than did those who seldom consumed these beverages (OR = 5.164; 95% CI, 1.866-14.297 and OR = 4.112; 95% CI, 1.857-9.107, respectively). Adolescents who consumed apple juice at least 5 times per week had a twofold greater odds of presence of allergic sensitization than did the seldom consumers (OR = 2.215; 95% CI, 1.178-4.164).
These findings provide some support for the hypothesis of a link between intake of excess free fructose beverages and allergic symptoms or allergic sensitization in children and adolescents.
本研究旨在探讨儿童和青少年过量饮用不含热量的果糖饮料与过敏之间的关系。
我们分析了 2005-2006 年全国健康和营养调查中 860 名 6-12 岁儿童和 1142 名 13-19 岁青少年的数据。采用 logistic 回归分析确定过量饮用不含热量的果糖饮料与过敏症状或过敏致敏之间的关系。
虽然结果模式不完全一致，但有些分析支持摄入过量不含热量的果糖饮料与过敏之间存在关联的假设。在控制潜在混杂因素后，每周至少饮用 5 次非节食水果饮料的儿童过敏致敏的几率是非节食水果饮料每周仅饮用 1-3 次的儿童的近 2.5 倍（OR=2.446；95%CI，1.583-3.780）。每周至少饮用 5 次或每周饮用 1-4 次过量不含热量的果糖饮料的青少年出现过敏症状的几率约为很少饮用此类饮料的青少年的 5 倍（OR=5.164；95%CI，1.866-14.297 和 OR=4.112；95%CI，1.857-9.107）。每周至少饮用 5 次苹果汁的青少年过敏致敏的几率是非节食水果饮料每周仅饮用 1-3 次的儿童的近 2 倍（OR=2.215；95%CI，1.178-4.164）。
这些发现为摄入过量不含热量的果糖饮料与儿童和青少年过敏症状或过敏致敏之间存在关联的假设提供了一定的支持。
