固氮酶中电子转移的控制。
Control of electron transfer in nitrogenase.
机构信息
Department of Chemistry and Biochemistry, Utah State University, 0300 Old Main Hill, Logan, UT 84322, USA.
Institute of Biological Chemistry, Washington State University, 287 Clark Hall, Pullman, WA 99164, USA.
出版信息
Curr Opin Chem Biol. 2018 Dec;47:54-59. doi: 10.1016/j.cbpa.2018.08.011. Epub 2018 Sep 8.
Abstract
The bacterial enzyme nitrogenase achieves the reduction of dinitrogen (N) to ammonia (NH) utilizing electrons, protons, and energy from the hydrolysis of ATP. Building on earlier foundational knowledge, recent studies provide molecular-level details on how the energy of ATP hydrolysis is utilized, the sequencing of multiple electron transfer events, and the nature of energy transduction across this large protein complex. Here, we review the state of knowledge about energy transduction in nitrogenase.
摘要
细菌酶氮还原酶利用来自 ATP 水解的电子、质子和能量将二氮 (N) 还原为氨 (NH)。在早期基础研究的基础上，最近的研究提供了关于 ATP 水解能量如何利用、多个电子转移事件的顺序以及穿过这个大型蛋白质复合物的能量转导性质的分子水平细节。在这里，我们回顾氮还原酶中能量转导的知识状态。
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本文引用的文献
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