Stengel Andreas, Taché Yvette
Department of Psychosomatic Medicine and Psychotherapy, University Hospital Tübingen, Tübingen, Germany.
Charité Center for Internal Medicine and Dermatology, Department for Psychosomatic Medicine, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.
Front Endocrinol (Lausanne). 2018 Aug 28;9:498. doi: 10.3389/fendo.2018.00498. eCollection 2018.
The gut-brain axis represents a bidirectional communication route between the gut and the central nervous system comprised of neuronal as well as humoral signaling. This system plays an important role in the regulation of gastrointestinal as well as homeostatic functions such as hunger and satiety. Recent years also witnessed an increased knowledge on the modulation of this axis under conditions of exogenous or endogenous stressors. The present review will discuss the alterations of neuroendocrine gut-brain signaling under conditions of stress and the respective implications for the regulation of food intake.
肠-脑轴代表了肠道与中枢神经系统之间的双向通信途径，由神经信号和体液信号组成。该系统在调节胃肠功能以及诸如饥饿和饱腹感等稳态功能方面发挥着重要作用。近年来，人们对外源性或内源性应激源条件下该轴的调节也有了更多了解。本综述将讨论应激条件下神经内分泌肠-脑信号的变化以及对食物摄入调节的相应影响。
