用于检测恶性疟原虫的灵敏且特异的DNA探针。

Mol Cell Biol. 1986 Jan;6(1):321-4. doi: 10.1128/mcb.6.1.321-324.1986.

The isolation and some characteristics of a very sensitive DNA probe for the detection of Plasmodium falciparum are described. The probe is species specific and represents a large, albeit variable, fraction of the genome in all the strains tested. In addition to its immediate practical uses for the detection and quantitation of parasites, the probe defines an interesting family of repeated sequences.

本文描述了一种用于检测恶性疟原虫的高灵敏度DNA探针的分离方法及其一些特性。该探针具有种属特异性，在所测试的所有菌株中，它代表了基因组中一个很大的部分，尽管存在变异。除了在检测和定量寄生虫方面的直接实际应用外，该探针还定义了一个有趣的重复序列家族。