Yang Elisa, Miao Shida, Zhong Jing, Zhang Zhiyong, Mills David K, Zhang Lijie Grace
Department of Mechanical and Aerospace Engineering, The George Washington University, Washington DC 20052, USA.
The University of Akron, Akron, 44304, USA.
Polym Rev (Phila Pa). 2018;58(4):668-687. doi: 10.1080/15583724.2018.1484761. Epub 2018 Sep 25.
Three-dimensional (3D) printing technologies enable not only faster bioconstructs development but also on-demand and customized manufacturing, offering patients a personalized biomedical solution. This emerging technique has a great potential for fabricating bioscaffolds with complex architectures and geometries and specifically tailored for use in regenerative medicine. The next major innovation in this area will be the development of biocompatible and histiogenic 3D printing materials with bio-based printable polymers. This review will briefly discuss 3D printing techniques and their current limitations, with a focus on novel bio-based polymers as 3D printing feedstock for clinical medicine and tissue regeneration.
三维（3D）打印技术不仅能够加快生物构建体的开发，还能实现按需定制制造，为患者提供个性化的生物医学解决方案。这项新兴技术在制造具有复杂结构和几何形状、专门用于再生医学的生物支架方面具有巨大潜力。该领域的下一个重大创新将是开发具有生物相容性和组织生成性的3D打印材料，这些材料采用生物基可打印聚合物制成。本文将简要讨论3D打印技术及其当前的局限性，重点关注作为临床医学和组织再生3D打印原料的新型生物基聚合物。
